Neuroprotective Effects of Activin A against Cerebral Ischemia/Reperfusion Injury in Mice by Enhancing Nrf2 Expression to Attenuate Neuronal Ferroptosis.

Wang, Fengzhi; Ma, Ming; Yang, Jiahui; Shi, Xiaohua; Wang, Jiaoqi; Xu, Zhongxin

Wang, Fengzhi; Ma, Ming; Yang, Jiahui; Shi, Xiaohua; Wang, Jiaoqi; Xu, Zhongxin.

Afiliación

Wang F; Department of Neurology, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Erdao District, Changchun 130033, China.
Ma M; Department of Neurology, People's Hospital of China Medical University, People's Hospital of Liaoning Province, 33 Wenyi Road, Shenhe District, Shenyang 110016, China.
Yang J; Department of Neurology, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Erdao District, Changchun 130033, China.
Shi X; Department of Neurology, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Erdao District, Changchun 130033, China.
Wang J; Department of Neurology, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Erdao District, Changchun 130033, China.
Xu Z; Department of Neurology, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Erdao District, Changchun 130033, China.

ACS Chem Neurosci ; 14(15): 2818-2826, 2023 08 02.

Article en En | MEDLINE | ID: mdl-37473431

Asunto(s)

Isquemia Encefálica; Ferroptosis; Fármacos Neuroprotectores; Daño por Reperfusión; Ratones; Animales; Fármacos Neuroprotectores/farmacología; Factor 2 Relacionado con NF-E2/metabolismo; Isquemia Encefálica/tratamiento farmacológico; Isquemia Encefálica/metabolismo; Infarto de la Arteria Cerebral Media/tratamiento farmacológico; Infarto de la Arteria Cerebral Media/metabolismo; Oxígeno; Glucosa; Daño por Reperfusión/tratamiento farmacológico; Daño por Reperfusión/metabolismo

Palabras clave

activin A (Act A); cerebral ischemia/reperfusion injury (CIRI); ferroptosis; nuclear factor erythroid-2-related factor 2 (Nrf2); oxygen-glucose deprivation/reoxygenation (OGD/R)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Daño por Reperfusión / Isquemia Encefálica / Fármacos Neuroprotectores / Ferroptosis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: ACS Chem Neurosci Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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