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Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial.
Polymeris, Alexandros A; Karwacki, Grzegorz M; Siepen, Bernhard M; Schaedelin, Sabine; Tsakiris, Dimitrios A; Stippich, Christoph; Guzman, Raphael; Nickel, Christian H; Sprigg, Nikola; Kägi, Georg; Vehoff, Jochen; Barinka, Filip; Thilemann, Sebastian; Maurer, Marina; Wagner, Benjamin; Traenka, Christopher; Gensicke, Henrik; De Marchis, Gian Marco; Bonati, Leo H; Fischer, Urs; Z'Graggen, Werner J; Nedeltchev, Krassen; Wegener, Susanne; Baumgartner, Philipp; Engelter, Stefan T; Seiffge, David J; Peters, Nils; Lyrer, Philippe A.
Afiliación
  • Karwacki GM; Department of Radiology and Nuclear Medicine, Luzerner Kantonsspital, Switzerland (G.M.K.).
  • Siepen BM; Department of Neurology, Inselspital, University Hospital and University of Bern, Switzerland (B.M.S., G.K., U.F., W.J.Z., D.J.S.).
  • Schaedelin S; Graduate School of Health Sciences, University of Bern, Switzerland (B.M.S.).
  • Tsakiris DA; Department of Clinical Research (S.S.), University Hospital Basel and University of Basel, Switzerland.
  • Stippich C; Division of Hematology, University Hospital Basel, Switzerland (D.A.T.).
  • Guzman R; Department of Neuroradiology and Radiology, Kliniken Schmieder, Allensbach, Germany (C.S.).
  • Nickel CH; Department of Neurosurgery (R.G.), University Hospital Basel and University of Basel, Switzerland.
  • Sprigg N; Department of Emergency Medicine (C.H.N.), University Hospital Basel and University of Basel, Switzerland.
  • Kägi G; Nottingham Stroke Trials Unit, University of Nottingham, United Kingdom (N.S.).
  • Vehoff J; Stroke Center, Klinik Hirslanden Zurich, Switzerland (F.B., N.P.).
  • Barinka F; Department of Neurology, Inselspital, University Hospital and University of Bern, Switzerland (B.M.S., G.K., U.F., W.J.Z., D.J.S.).
  • Thilemann S; Department of Neurology and Stroke Center, Cantonal Hospital St. Gallen, Switzerland (G.K., J.V.).
  • Maurer M; Department of Neurology and Stroke Center, Cantonal Hospital St. Gallen, Switzerland (G.K., J.V.).
  • Wagner B; Stroke Center, Klinik Hirslanden Zurich, Switzerland (F.B., N.P.).
  • Traenka C; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • Gensicke H; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • De Marchis GM; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • Bonati LH; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • Fischer U; Neurology and Neurorehabilitation, University Department of Geriatric Medicine Felix Platter, University of Basel, Switzerland (C.T., H.G., S.T.E., N.P.).
  • Z'Graggen WJ; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • Nedeltchev K; Neurology and Neurorehabilitation, University Department of Geriatric Medicine Felix Platter, University of Basel, Switzerland (C.T., H.G., S.T.E., N.P.).
  • Wegener S; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • Baumgartner P; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • Engelter ST; Reha Rheinfelden, Switzerland (L.H.B.).
  • Seiffge DJ; Department of Neurology and Stroke Center (A.A.P., S.T., M.M., B.W., C.T., H.G., G.M.D.M., L.H.B., U.F., S.T.E., D.J.S., N.P., P.A.L.), University Hospital Basel and University of Basel, Switzerland.
  • Peters N; Department of Neurology, Inselspital, University Hospital and University of Bern, Switzerland (B.M.S., G.K., U.F., W.J.Z., D.J.S.).
  • Lyrer PA; Department of Neurology, Inselspital, University Hospital and University of Bern, Switzerland (B.M.S., G.K., U.F., W.J.Z., D.J.S.).
Stroke ; 54(9): 2223-2234, 2023 09.
Article en En | MEDLINE | ID: mdl-37466000

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tromboembolia / Ácido Tranexámico / Hemostáticos / Antifibrinolíticos Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Stroke Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tromboembolia / Ácido Tranexámico / Hemostáticos / Antifibrinolíticos Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Stroke Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos