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Structure-based design, optimization of lead, synthesis, and biological evaluation of compounds active against Trypanosoma cruzi.
de Almeida, Gleybson Correia; de Oliveira, Gerliny Bezerra; da Silva Monte, Zenaide; Costa, Érick Caique Santos; da Silva Falcão, Emerson Peter; Scotti, Luciana; Scotti, Marcus Tullius; Oliveira Silva, Ricardo; Pereira, Valéria Rêgo Alves; da Silva, Elis Dionisio; Junior, Policarpo Ademar Sales; de Andrade Cavalcante, Marton Kaique; de Melo, Sebastião José.
Afiliación
  • de Almeida GC; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Federal University of Pernambuco/UFPE, Recife, Brazil.
  • de Oliveira GB; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Federal University of Pernambuco/UFPE, Recife, Brazil.
  • da Silva Monte Z; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Federal University of Pernambuco/UFPE, Recife, Brazil.
  • Costa ÉCS; Postgraduate Program in Biological Sciences, Department of Biosciences, Federal University of Pernambuco/UFPE, Recife, Brazil.
  • da Silva Falcão EP; Vitória Academic Center, Federal University of Pernambuco - St Alto do Reservatório, Vitória de Santo Antão, Brazil.
  • Scotti L; Laboratory of Cheminformatics, Program of Natural and Synthetic Bioactive Products (PgPNSB), Health Sciences Center, Federal University of Paraíba, João Pessoa, Brazil.
  • Scotti MT; Laboratory of Cheminformatics, Program of Natural and Synthetic Bioactive Products (PgPNSB), Health Sciences Center, Federal University of Paraíba, João Pessoa, Brazil.
  • Oliveira Silva R; Department of Fundamental Chemistry, Center for Exact and Natural Sciences, Federal University of Pernambuco, Av. Journalist Anibal Fernandes, Recife, Brazil.
  • Pereira VRA; Aggeu Magalhães Research Center, Oswaldo Cruz Foundation, Federal University of Pernambuco - Campus da Av. Prof. Moraes Rego, Recife, Brazil.
  • da Silva ED; Aggeu Magalhães Research Center, Oswaldo Cruz Foundation, Federal University of Pernambuco - Campus da Av. Prof. Moraes Rego, Recife, Brazil.
  • Junior PAS; Aggeu Magalhães Research Center, Oswaldo Cruz Foundation, Federal University of Pernambuco - Campus da Av. Prof. Moraes Rego, Recife, Brazil.
  • de Andrade Cavalcante MK; Aggeu Magalhães Research Center, Oswaldo Cruz Foundation, Federal University of Pernambuco - Campus da Av. Prof. Moraes Rego, Recife, Brazil.
  • de Melo SJ; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Federal University of Pernambuco/UFPE, Recife, Brazil.
Chem Biol Drug Des ; 102(4): 843-856, 2023 10.
Article en En | MEDLINE | ID: mdl-37455325
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tripanocidas / Trypanosoma cruzi / Enfermedad de Chagas Límite: Animals / Humans Idioma: En Revista: Chem Biol Drug Des Asunto de la revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tripanocidas / Trypanosoma cruzi / Enfermedad de Chagas Límite: Animals / Humans Idioma: En Revista: Chem Biol Drug Des Asunto de la revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido