Discovery and Characterization of PROTACs Targeting Tissue Transglutaminase (TG2).

Valdivia, Andres; Vagadia, Purav P; Guo, Guangxu; O'Brien, Eilidh; Matei, Daniela; Schiltz, Gary E

Valdivia, Andres; Vagadia, Purav P; Guo, Guangxu; O'Brien, Eilidh; Matei, Daniela; Schiltz, Gary E.

Afiliación

Valdivia A; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.
Vagadia PP; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Guo G; WuXi AppTec, Shanghai 200131, People's Republic of China.
O'Brien E; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.
Matei D; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.
Schiltz GE; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States.

J Med Chem ; 66(14): 9445-9465, 2023 07 27.

Article en En | MEDLINE | ID: mdl-37449845

Asunto(s)

Proteína Glutamina Gamma Glutamiltransferasa 2; Transglutaminasas; Femenino; Humanos; Quimera Dirigida a la Proteólisis; Proteínas de Unión al GTP/metabolismo; Adhesión Celular

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transglutaminasas / Proteína Glutamina Gamma Glutamiltransferasa 2 Límite: Female / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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