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The impact of high intensity interval training in a diverse group of cancer survivors: CAPABLE, a pilot study.
Beebe-Dimmer, Jennifer L; Finlay, David G; Ruterbusch, Julie J; Baird, Tara; Simon, Michael S; Abrams, Judith; Harper, Felicity W K; Podgorski, Izabela; Heath, Elisabeth I.
Afiliación
  • Beebe-Dimmer JL; Wayne State University, School of Medicine Departments of Oncology, Detroit, MI 48201, United States.
  • Finlay DG; Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, United States.
  • Ruterbusch JJ; Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, United States.
  • Baird T; Wayne State University, School of Medicine Departments of Oncology, Detroit, MI 48201, United States.
  • Simon MS; Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, United States.
  • Abrams J; Wayne State University, School of Medicine Departments of Oncology, Detroit, MI 48201, United States.
  • Harper FWK; Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, United States.
  • Podgorski I; Wayne State University, School of Medicine Departments of Oncology, Detroit, MI 48201, United States.
  • Heath EI; Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, United States.
Prev Med Rep ; 35: 102288, 2023 Oct.
Article en En | MEDLINE | ID: mdl-37449003
Purpose: Given the well-documented benefits of regular exercise to cancer survivors, current American Cancer Society guidelines recommend that patients engage in a minimum of 150 min per week of moderate-to-vigorous physical activity with a minimum of two days of strength training. However, few survivors meet this goal, particularly among minorities. Methods: The CAPABLE study is a single-arm, pilot exercise intervention that introduced 48 cancer survivors to a high intensity interval and strength training program three days a week for 12 weeks. We evaluated the impact of this unique training method on bodyweight, % body fat, serum markers correlated with an adverse cardiometabolic profile and health-related quality of life (HRQoL). Measures were summarized at baseline and program exit. Paired t-tests were used to assess change in each of these measures over time. Results: We observed losses in weight, body mass index, and % body fat, and glycosylated hemoglobin (HbA1c) levels over 12-weeks. There were also clinically meaningful improvements in reported overall HRQoL (FACTG total change +9.5 (95% CI, 4.6, 14.4)) and in each one of the individual domains (physical, social, emotional, and functional well-being). Conclusions: We observed meaningful improvements in body composition, HbA1c and quality of life over 12 weeks among cancer survivors participating in a high-intensity interval training program. Future work will include a control arm for comparison and address barriers to participation and adherence which will be important in using this intervention and others like it to improve outcomes and reduce cancer health disparities.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline Aspecto: Patient_preference Idioma: En Revista: Prev Med Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline Aspecto: Patient_preference Idioma: En Revista: Prev Med Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos