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Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.
Leit, Silvana; Greenwood, Jeremy; Carriero, Samantha; Mondal, Sayan; Abel, Robert; Ashwell, Mark; Blanchette, Heather; Boyles, Nicholas A; Cartwright, Mark; Collis, Alan; Feng, Shulu; Ghanakota, Phani; Harriman, Geraldine C; Hosagrahara, Vinayak; Kaila, Neelu; Kapeller, Rosanna; Rafi, Salma B; Romero, Donna L; Tarantino, Paul M; Timaniya, Jignesh; Toms, Angela V; Wester, Ronald T; Westlin, William; Srivastava, Bhaskar; Miao, Wenyan; Tummino, Peter; McElwee, Joshua J; Edmondson, Scott D; Masse, Craig E.
Afiliación
  • Leit S; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Greenwood J; Schrödinger, Inc., 1540 Broadway, New York, New York 10036, United States.
  • Carriero S; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Mondal S; Schrödinger, Inc., 1540 Broadway, New York, New York 10036, United States.
  • Abel R; Schrödinger, Inc., 1540 Broadway, New York, New York 10036, United States.
  • Ashwell M; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Blanchette H; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Boyles NA; Schrödinger, Inc., 1540 Broadway, New York, New York 10036, United States.
  • Cartwright M; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Collis A; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Feng S; Schrödinger, Inc., 1540 Broadway, New York, New York 10036, United States.
  • Ghanakota P; Schrödinger, Inc., 1540 Broadway, New York, New York 10036, United States.
  • Harriman GC; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Hosagrahara V; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Kaila N; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Kapeller R; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Rafi SB; Schrödinger, Inc., 1540 Broadway, New York, New York 10036, United States.
  • Romero DL; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Tarantino PM; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Timaniya J; Piramal Pharma Solutions, Plot No. 18, Pharmez, Ahmedabad 382215, Gujarat, India.
  • Toms AV; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Wester RT; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Westlin W; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Srivastava B; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Miao W; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Tummino P; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • McElwee JJ; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Edmondson SD; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
  • Masse CE; Nimbus Therapeutics, 22 Boston Wharf Road, Floor 9, Boston, Massachusetts 02210, United States.
J Med Chem ; 66(15): 10473-10496, 2023 08 10.
Article en En | MEDLINE | ID: mdl-37427891
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Psoriasis / Enfermedades Autoinmunes Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Psoriasis / Enfermedades Autoinmunes Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos