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A mechanistic updated overview on Cepharanthine as potential anticancer agent.
Wang, YingZheng; Wang, Tong; Wang, HuaXin; Liu, WeiDong; Li, Xiao; Wang, XiaoYan; Zhang, YaNan.
Afiliación
  • Wang Y; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province 250355, China.
  • Wang T; School of Nursing, Shandong University of Traditional Chinese Medicine, Jinan, Shangdong Province 250355, China.
  • Wang H; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province 250355, China.
  • Liu W; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province 250355, China.
  • Li X; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province 250355, China.
  • Wang X; College of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province 250355, China.
  • Zhang Y; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province 250355, China. Electronic address: zyn8326@163.com.
Biomed Pharmacother ; 165: 115107, 2023 Sep.
Article en En | MEDLINE | ID: mdl-37423171
The antitumor effects of traditional drugs have received increasing attention and active antitumor components extracted from traditional drugs have shown good efficacy with minimal adverse events. Cepharanthine(CEP for short) is an active component derived from the Stephania plants of Menispermaceae, which can regulate multiple signaling pathways alone or in combination with other therapeutic drugs to inhibit tumor cell proliferation, induce apoptosis, regulate autophagy, and inhibit angiogenesis, thereby inhibiting tumor progression. Therefore, we retrieved studies concerning CEP's antitumor effects in recent years and summarized the antitumor mechanism and targets, in order to gain new insights and establish a theoretical basis for further development and application of CEP.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bencilisoquinolinas / Benzodioxoles / Antineoplásicos Límite: Humans Idioma: En Revista: Biomed Pharmacother Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bencilisoquinolinas / Benzodioxoles / Antineoplásicos Límite: Humans Idioma: En Revista: Biomed Pharmacother Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia