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External stenting for saphenous vein grafts in coronary artery bypass grafting: A meta-analysis.
Chen, Huiru; Wang, Zilan; Si, Ke; Wu, Xiaoxiao; Ni, Hanyu; Tang, Yanbing; Liu, Wei; Wang, Zhong.
Afiliación
  • Chen H; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Jiangsu Province, China.
  • Wang Z; Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Si K; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Jiangsu Province, China.
  • Wu X; Department of Cardiovascular Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Ni H; Suzhou Medical College of Soochow University, Suzhou, China.
  • Tang Y; Suzhou Medical College of Soochow University, Suzhou, China.
  • Liu W; Suzhou Medical College of Soochow University, Suzhou, China.
  • Wang Z; Department of Medicine, The Tianjin North China Hospital, Tianjin, China.
Eur J Clin Invest ; 53(11): e14046, 2023 Nov.
Article en En | MEDLINE | ID: mdl-37395498
OBJECTIVES: Autologous saphenous vein grafts (SVGs) are the most commonly used bypass conduits in coronary artery bypass grafting (CABG) with multivessel coronary artery disease. Although external support devices for SVGs have shown promising outcomes, the overall efficacy and safety remains controversial. We aimed to evaluate external stenting for SVGs in CABG versus non-stented SVGs. METHODS: MEDLINE, EMBASE, Cochrane Library and clinicaltrails.gov were searched for randomized controlled trials (RCTs) to evaluate external-stented SVGs versus non-stented SVGs in CABG up to 31 August 2022. The risk ratio and mean difference with 95% confidence interval were analysed. The primary efficacy outcomes included intimal hyperplasia area and thickness. The secondary efficacy outcomes were graft failure (≥50% stenosis) and lumen diameter uniformity. RESULTS: We pooled 438 patients from three RCTs. The external stented SVGs group showed significant reductions in intimal hyperplasia area (MD: -0.78, p < 0.001, I2 = 0%) and thickness (MD: -0.06, p < 0.001, I2 = 0%) compared to the non-stented SVGs group. Meanwhile, external support devices improved lumen uniformity with Fitzgibbon I classification (risk ratio (RR):1.1595, p = 0.05, I2 = 0%). SVG failure rates were not increased in the external stented SVGs group during the short follow-up period (RR: 1.14, p = 0.38, I2 = 0%). Furthermore, the incidences of mortality and major cardiac and cerebrovascular events were consistent with previous reports. CONCLUSIONS: External support devices for SVGs significantly reduced the intimal hyperplasia area and thickness, and improved the lumen uniformity, assessed with the Fitzgibbon I classification. Meanwhile, they did not increase the overall SVG failure rate.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Systematic_reviews Idioma: En Revista: Eur J Clin Invest Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Systematic_reviews Idioma: En Revista: Eur J Clin Invest Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido