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Low bone mineral density is found in low weight female youth with avoidant/restrictive food intake disorder and associated with higher PYY levels.
Sella, Aluma Chovel; Becker, Kendra R; Slattery, Meghan; Hauser, Kristine; Asanza, Elisa; Stern, Casey; Kuhnle, Megan; Micali, Nadia; Eddy, Kamryn T; Misra, Madhusmita; Thomas, Jennifer J; Lawson, Elizabeth A.
Afiliación
  • Sella AC; Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
  • Becker KR; Division of Pediatric Endocrinology, Mass General Hospital for Children, Boston, MA, USA.
  • Slattery M; Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, MA, USA.
  • Hauser K; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
  • Asanza E; Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
  • Stern C; Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
  • Kuhnle M; Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
  • Micali N; Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, MA, USA.
  • Eddy KT; Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
  • Misra M; Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Thomas JJ; Department of Pediatrics Gynecology and Obstetrics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  • Lawson EA; Mental Health Services in the Capital Region of Denmark, Eating Disorders Research Unit, Psychiatric Centre Ballerup, Ballerup, Denmark.
J Eat Disord ; 11(1): 106, 2023 Jul 01.
Article en En | MEDLINE | ID: mdl-37393263
Avoidant/restrictive food Intake disorder (ARFID) is a condition characterized by lack of interest in eating/food, sensory sensitivity and/or fear of aversive consequences of eating. It is associated with low weight and undernutrition, which can lead to medical complications. Specifically, low weight in patients with ARFID raises concerns of impaired bone health. In this study, we compared bone mineral density (BMD), a measure of bone health, in 14 low-weight females with ARFID and 20 healthy females 10­23 years old. We also examined the association between BMD and peptide YY (PYY), a hormone that induces satiety and inhibits bone formation. A strong negative association between bone health and PYY was previously reported in females with anorexia nervosa. Thus, we hypothesized a similar association in low weight females with ARFID. We found that BMD may be lower in low-weight females with ARFID than in healthy females and that higher PYY levels are associated with lower BMD at some but not all sites. We concluded that bone health may be a concern in low-weight females with ARFID. This finding is important as low BMD raises concerns for increased fracture risk, which in turn could have a detrimental effect on quality of life.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Aspecto: Patient_preference Idioma: En Revista: J Eat Disord Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Aspecto: Patient_preference Idioma: En Revista: J Eat Disord Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido