Zinc Ameliorates Cadmium-Induced Immunotoxicity by Modulating Splenic Immunosuppressive Indoleamine 2,3-Dioxygenase Activity, Hematological Indices, and CD4<sup>+</sup> T Cells via Inhibition of Cadmium Uptake in Male Wistar Rats.

Ebokaiwe, Azubuike Peter; Olasehinde, Olusanya; Chimezie, Iyiagwor P; Odobi, Ushang R; Nvene, Chiamaka; Faith, Ekoh

Zinc Ameliorates Cadmium-Induced Immunotoxicity by Modulating Splenic Immunosuppressive Indoleamine 2,3-Dioxygenase Activity, Hematological Indices, and CD4⁺ T Cells via Inhibition of Cadmium Uptake in Male Wistar Rats.

Ebokaiwe, Azubuike Peter; Olasehinde, Olusanya; Chimezie, Iyiagwor P; Odobi, Ushang R; Nvene, Chiamaka; Faith, Ekoh.

Afiliación

Ebokaiwe AP; Toxicology and Immunotherapy Research Unit, Department of Biochemistry, Alex Ekwueme Federal University Ndufu Alike, PMB 1010, Abakaliki, Ebonyi State, Nigeria. petazk@yahoo.com.
Olasehinde O; Department of Biochemistry, University of Benin, Benin City, Nigeria.
Chimezie IP; Toxicology and Immunotherapy Research Unit, Department of Biochemistry, Alex Ekwueme Federal University Ndufu Alike, PMB 1010, Abakaliki, Ebonyi State, Nigeria.
Odobi UR; Toxicology and Immunotherapy Research Unit, Department of Biochemistry, Alex Ekwueme Federal University Ndufu Alike, PMB 1010, Abakaliki, Ebonyi State, Nigeria.
Nvene C; Toxicology and Immunotherapy Research Unit, Department of Biochemistry, Alex Ekwueme Federal University Ndufu Alike, PMB 1010, Abakaliki, Ebonyi State, Nigeria.
Faith E; Toxicology and Immunotherapy Research Unit, Department of Biochemistry, Alex Ekwueme Federal University Ndufu Alike, PMB 1010, Abakaliki, Ebonyi State, Nigeria.

Biol Trace Elem Res ; 202(3): 1140-1149, 2024 Mar.

Article en En | MEDLINE | ID: mdl-37392360

Asunto(s)

Agua Potable; Zinc; Ratas; Masculino; Humanos; Animales; Ratas Wistar; Zinc/farmacología; Zinc/metabolismo; Cadmio/farmacología; Indolamina-Pirrol 2,3,-Dioxigenasa/metabolismo; Indolamina-Pirrol 2,3,-Dioxigenasa/farmacología; Bazo/metabolismo; Estrés Oxidativo; Linfocitos T/metabolismo; Linfocitos T CD4-Positivos

Palabras clave

Immunotoxicity; Indoleamine 2,3-dioxygenase; Oxido-inflammatory stress; Spleen

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Zinc / Agua Potable Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Biol Trace Elem Res Año: 2024 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google