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Response to comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice'.
Li, Yutian; Sarma, Anish A; Lee, Iris T; Tan, Fayth Hui; Abrams, Michael J; Condiotte, Zevin J; Heithe, Martin; Raffiee, Misha; Dabiri, John O; Gold, David A; Goentoro, Lea.
Afiliación
  • Li Y; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Sarma AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Lee IT; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Tan FH; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Abrams MJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Condiotte ZJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Heithe M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Raffiee M; Graduate Aerospace Laboratories and Mechanical Engineering, California Institute of Technology, Pasadena, United States.
  • Dabiri JO; Graduate Aerospace Laboratories and Mechanical Engineering, California Institute of Technology, Pasadena, United States.
  • Gold DA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  • Goentoro L; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Elife ; 122023 Jun 22.
Article en En | MEDLINE | ID: mdl-37347515
Previously we reported evidence that a regenerative response in the appendages of moon jellyfish, fruit flies, and mice can be promoted by nutrient modulation (Abrams et al., 2021). Sustar and Tuthill subsequently reported that they had not been able to reproduce the induced regenerative response in flies (Sustar and Tuthill, 2023). Here we discuss that differences in the amputation method, treatment concentrations, age of the animals, and stress management explain why they did not observe a regenerative response in flies. Typically, 30-50% of treated flies showed response in our assay.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Drosophila / Escifozoos Límite: Animals Idioma: En Revista: Elife Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Drosophila / Escifozoos Límite: Animals Idioma: En Revista: Elife Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido