Your browser doesn't support javascript.
loading
Impact of hypoalbuminemia on in-hospital mortality in patients with takotsubo syndrome: A multicenter registry of the Tokyo Cardiovascular Care Unit Network.
Watanabe, Yukihiro; Yoshikawa, Tsutomu; Isogai, Toshiaki; Sakata, Konomi; Yamaguchi, Tetsuo; Arao, Kenshiro; Takaoka, Yoshimitsu; Inohara, Taku; Imori, Yoichi; Mochizuki, Hiroki; Yamamoto, Takeshi; Asai, Kuniya; Nagao, Ken; Takayama, Morimasa.
Afiliación
  • Watanabe Y; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan. Electronic address: s10-112yw@nms.ac.jp.
  • Yoshikawa T; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Isogai T; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Sakata K; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Yamaguchi T; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Arao K; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Takaoka Y; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Inohara T; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Imori Y; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
  • Mochizuki H; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Yamamoto T; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
  • Asai K; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
  • Nagao K; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
  • Takayama M; Tokyo Cardiovascular Care Unit Network Scientific Committee, Tokyo, Japan.
J Cardiol ; 82(5): 356-362, 2023 11.
Article en En | MEDLINE | ID: mdl-37343932
BACKGROUND: Hypoalbuminemia is common in critically ill patients and is associated with poor outcomes. However, the relationship between serum albumin levels and clinical outcomes in patients with takotsubo syndrome remains unclear. We examined the impact of hypoalbuminemia on in-hospital mortality in patients with takotsubo syndrome. METHODS: Using the multicenter registry of the Tokyo Cardiovascular Care Unit Network between January 2017 and December 2020, we identified 631 eligible patients with takotsubo syndrome (median age, 78 years; male proportion, 22 %) and documented serum albumin levels at admission, which were used to allocate patients to hypoalbuminemia (serum albumin <3.5 g/dL) or normal albumin (serum albumin ≥3.5 g/dL) groups. Patient characteristics and in-hospital mortality were compared between the groups. RESULTS: Hypoalbuminemia was detected in 200 (32 %) patients at admission. The hypoalbuminemia group was older and had a higher proportion of men and preceding physical triggers than the normal albumin group. In-hospital all-cause mortality was greater in the hypoalbuminemia group than in the normal albumin group (9.5 % vs. 1.9 %, p < 0.001). Both cardiac (3.0 % vs. 0.5 %, p = 0.015) and non-cardiac (6.5 % vs. 1.4 %, p = 0.002) mortality was greater in the hypoalbuminemia group. In multivariable logistic regression analysis, hypoalbuminemia was independently associated with increased in-hospital mortality, even after adjusting for confounders, including age, sex, and triggering events (odds ratio, 3.23; 95 % confidence interval, 1.31-7.95; p = 0.011). CONCLUSIONS: In patients with takotsubo syndrome, hypoalbuminemia is a common comorbidity and is associated with a substantial risk of in-hospital death. Close monitoring and comprehensive critical care are required in these patients.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipoalbuminemia / Cardiomiopatía de Takotsubo Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans / Male País/Región como asunto: Asia Idioma: En Revista: J Cardiol Asunto de la revista: CARDIOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipoalbuminemia / Cardiomiopatía de Takotsubo Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans / Male País/Región como asunto: Asia Idioma: En Revista: J Cardiol Asunto de la revista: CARDIOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos