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Optically stimulated luminescence detectors for dosimetry and LET measurements in light ion beams.
Christensen, Jeppe Brage; Muñoz, Iván Domingo; Bassler, Niels; Stengl, Christina; Bossin, Lily; Togno, Michele; Safai, Sairos; Jäkel, Oliver; Yukihara, Eduardo Gardenali.
Afiliación
  • Christensen JB; Department of Radiation Safety and Security, Paul Scherrer Institute, Villigen PSI, Switzerland.
  • Muñoz ID; Department of Physics and Astronomy, University of Heidelberg, Heidelberg, Germany.
  • Bassler N; Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Stengl C; Heidelberg Institute for Radiation Oncology (HIRO), National Center for Radiation Research in Oncology, Heidelberg, Germany.
  • Bossin L; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Togno M; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
  • Safai S; Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Jäkel O; Heidelberg Institute for Radiation Oncology (HIRO), National Center for Radiation Research in Oncology, Heidelberg, Germany.
  • Yukihara EG; Faculty of Medicine, University of Heidelberg, Heidelberg, Germany.
Phys Med Biol ; 68(15)2023 07 21.
Article en En | MEDLINE | ID: mdl-37336242
Objective.This work investigates the use of Al2O3:C and Al2O3:C,Mg optically stimulated luminescence (OSL) detectors to determine both the dose and the radiation quality in light ion beams. The radiation quality is here expressed through either the linear energy transfer (LET) or the closely related metricQeff, which depends on the particle's speed and effective charge. The derived LET andQeffvalues are applied to improve the dosimetry in light ion beams.Approach.OSL detectors were irradiated in mono-energetic1H-,4He-,12C-, and16O-ion beams. The OSL signal is associated with two emission bands that were separated using a pulsed stimulation technique and subjected to automatic corrections based on reference irradiations. Each emission band was investigated independently for dosimetry, and the ratio of the two emission intensities was parameterized as a function of fluence- and dose-averaged LET, as well asQeff. The determined radiation quality was subsequently applied to correct the dose for ionization quenching.Main results.For both materials, theQeffdeterminations in1H- and4He-ion beams are within 5 % of the Monte Carlo simulated values. Using the determined radiation quality metrics to correct the nonlinear (ionization quenched) detector response leads to doses within 2 % of the reference doses.Significance.Al2O3:C and Al2O3:C,Mg OSL detectors are applicable for dosimetry and radiation quality estimations in1H- and4He-ions. Only Al2O3:C,Mg shows promising results for dosimetry in12C-ions. Across both materials and the investigated ions, the estimatedQeffvalues were less sensitive to the ion types than the estimated LET values were. The reduced uncertainties suggest new possibilities for simultaneously estimating the physical and biological dose in particle therapy with OSL detectors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transferencia Lineal de Energía / Dosimetría con Luminiscencia Ópticamente Estimulada Idioma: En Revista: Phys Med Biol Año: 2023 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transferencia Lineal de Energía / Dosimetría con Luminiscencia Ópticamente Estimulada Idioma: En Revista: Phys Med Biol Año: 2023 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido