Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation.

Negi, Sushmita; Tandel, Nikunj; Sharma, Prakriti; Kumar, Rajinder; Tyagi, Rajeev K

Negi, Sushmita; Tandel, Nikunj; Sharma, Prakriti; Kumar, Rajinder; Tyagi, Rajeev K.

Afiliación

Negi S; Division of Cell Biology and Immunology, Biomedical Parasitology and Translational-immunology Lab, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh-160036, India; Academy of Scientific and Innovation Research (AcSIR), Ghaziabad 201002, India.
Tandel N; Institute of Science, Nirma University, SG highway, Ahmedabad-382481, India.
Sharma P; Division of Cell Biology and Immunology, Biomedical Parasitology and Translational-immunology Lab, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh-160036, India.
Kumar R; Division of Cell Biology and Immunology, Biomedical Parasitology and Translational-immunology Lab, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh-160036, India.
Tyagi RK; Division of Cell Biology and Immunology, Biomedical Parasitology and Translational-immunology Lab, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh-160036, India; Academy of Scientific and Innovation Research (AcSIR), Ghaziabad 201002, India. Electronic address: rajeevtyagi@imtec

Drug Discov Today ; 28(8): 103671, 2023 08.

Article en En | MEDLINE | ID: mdl-37330038

Asunto(s)

Antirreumáticos; Artritis Experimental; Artritis Reumatoide; Ratones; Animales; Metotrexato/farmacología; Metotrexato/uso terapéutico; Antirreumáticos/farmacología; Antirreumáticos/uso terapéutico; Artritis Reumatoide/tratamiento farmacológico; Inflamación/tratamiento farmacológico; Artritis Experimental/tratamiento farmacológico; Artritis Experimental/metabolismo; Quimioterapia Combinada

Palabras clave

Methotrexate; aceclofenac; combination drug regimen; humanized mice; inflammation; nanoparticle; rheumatoid arthritis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Experimental / Artritis Reumatoide / Antirreumáticos Límite: Animals Idioma: En Revista: Drug Discov Today Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

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