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Gastrointestinal involvement in gallbladder cancer: Computed tomography findings and proposal of a classification system.
Soundararajan, Raghuraman; Vanka, Srivardhan; Gupta, Pankaj; Chhabra, Manika; Rana, Pratyaksha; Gulati, Ajay; Das, Chandan K; Gupta, Parikshaa; Saikia, Uma Nahar; Yadav, Thakur Deen; Gupta, Vikas; Kaman, Lileswar; Singh, Harjeet; Irrinki, Santosh; Dutta, Usha; Sandhu, Manavjit Singh.
Afiliación
  • Soundararajan R; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Vanka S; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Gupta P; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India. pankajgupta959@gmail.com.
  • Chhabra M; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Rana P; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Gulati A; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Das CK; Department of Clinical Hematology and Medical Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Gupta P; Department of Cytology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Saikia UN; Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Yadav TD; Department of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Gupta V; Department of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Kaman L; Department General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Singh H; Department of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Irrinki S; Department General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Dutta U; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
  • Sandhu MS; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
Indian J Gastroenterol ; 42(5): 708-712, 2023 10.
Article en En | MEDLINE | ID: mdl-37318744
BACKGROUND: There is relatively scarce data on the computed tomography (CT) detection of gastrointestinal (GI) involvement in gallbladder cancer (GBC). We aim to assess the GI involvement in GBC on CT and propose a CT-based classification. METHODS: This retrospective study comprized consecutive patients with GBC who underwent contrast-enhanced computed tomography (CECT) for staging between January 2019 and April 2022. Two radiologists evaluated the CT images independently for the morphological type of GBC and the presence of GI involvement. GI involvement was classified into probable involvement, definite involvement and GI fistulization. The incidence of GI involvement and the association of GI involvement with the morphological type of GBC was evaluated. In addition, the inter-observer agreement for GI involvement was assessed. RESULTS: Over the study period, 260 patients with GBC were evaluated. Forty-three (16.5%) patients had GI involvement. Probable GI involvement, definite GI involvement and GI fistulization were seen in 18 (41.9%), 19 (44.2%) and six (13.9%) patients, respectively. Duodenum was the most common site of involvement (55.8%), followed by hepatic flexure (23.3%), antropyloric region (9.3%) and transverse colon (2.3%). There was no association between GI involvement and morphological type of GBC. There was substantial to near-perfect agreement between the two radiologists for the overall GI involvement (k = 0.790), definite GI involvement (k = 0.815) and GI fistulization (k = 0.943). There was moderate agreement (k = 0.567) for probable GI involvement. CONCLUSION: GBC frequently involves the GI tract and CT can be used to categorize the GI involvement. However, the proposed CT classification needs validation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Vesícula Biliar Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Indian J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: India Pais de publicación: India
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Vesícula Biliar Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Indian J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: India Pais de publicación: India