Inhibition of OAT1/3 and CMPF uptake attenuates myocardial ischemia-induced chronic heart failure via decreasing fatty acid oxidation and the therapeutic effects of ruscogenin.

Lai, Qiong; Zhu, Xiaozhou; Zhang, Lu; Kou, Junping; Liu, Fuming; Yu, Boyang; Li, Fang

Lai, Qiong; Zhu, Xiaozhou; Zhang, Lu; Kou, Junping; Liu, Fuming; Yu, Boyang; Li, Fang.

Afiliación

Lai Q; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Zhu X; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Zhang L; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Kou J; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Liu F; Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Yu B; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Li F; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China. Electronic address: lifangcpu@163.com.

Transl Res ; 261: 1-15, 2023 11.

Article en En | MEDLINE | ID: mdl-37315712

Asunto(s)

Enfermedad de la Arteria Coronaria; Insuficiencia Cardíaca; Isquemia Miocárdica; Humanos; Ratones; Animales; Anciano; Simulación del Acoplamiento Molecular; Insuficiencia Cardíaca/tratamiento farmacológico; Insuficiencia Cardíaca/etiología; Enfermedad Crónica; Ácidos Grasos

Palabras clave

3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid; OAT1/3; chronic heart failure; fatty acid oxidation; ruscogenin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Isquemia Miocárdica / Insuficiencia Cardíaca Tipo de estudio: Etiology_studies / Prognostic_studies / Screening_studies Límite: Aged / Animals / Humans Idioma: En Revista: Transl Res Asunto de la revista: MEDICINA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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