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Relationship between Adipocytokines, Nontraditional Anthropometric Indices and Coronary Heart Disease Risk in Diabetic Patients.
Fajkic, Almir; Lepara, Orhan; Dervisevic, Amela; Kurtovic, Avdo; Dzubur, Alen; Ejubovic, Malik; Dozic, Ada; Mujakovic, Aida; Jahic, Rijad.
Afiliación
  • Fajkic A; Department of Pathophysiology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
  • Lepara O; Department of Human Physiology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
  • Dervisevic A; Department of Human Physiology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
  • Kurtovic A; Primary Healthcare Centre Gracanica, Bosnia and Herzegovina.
  • Dzubur A; Department for Cardiology, Clinic for Heart, Blood Vessel and Rheumatic Diseases. Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
  • Ejubovic M; Department of Internal Diseases, Cantonal Hospital Zenica, Bosnia and Herzegovina.
  • Dozic A; General Hospital "Prim. dr Abdulah Nakas" Sarajevo, Bosnia and Herzegovina.
  • Mujakovic A; General Hospital "Prim. dr Abdulah Nakas" Sarajevo, Bosnia and Herzegovina.
  • Jahic R; Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Curr Health Sci J ; 48(4): 365-372, 2022.
Article en En | MEDLINE | ID: mdl-37304801
INTRODUCTION: Diabetes mellitus type 2 (T2DM) significantly increase the risk of cardiovascular (CV) disease morbidity and mortality. This study aimed to evaluate the potential of some novel anthropometric indices and adipocytokines to evaluate CV risk among T2DM patients. METHODS: A total of 112 patients (men, 57; women, 55) with T2DM visiting Family Medicine and Endocrine counseling in the area of Health centers of Sarajevo Canton were included in this study. The sera samples were analyzed for fasting blood glucose (FBG), HbA1c, lipid profile parameters, adiponectin, and resistin levels. The Adiponectin/Resistin Index (A/R Index) was estimated using the formula. The novel anthropometric measurements, including the Conicity index (CI), Lipid Accumulation Product (LAP), visceral adiposity index (VAI), abdominal volume index (AVI), and Body adiposity index (BAI) were estimated. The 10-year risk for coronary heart disease (CHD) and fatal coronary heart disease (fCHD) is calculated by using UKPDS Risk software. RESULTS: The adiponectin was shown as a statistically significant negative association with CHD in female subjects, and the A/R index as a statistically significant association with CHD and fCHD in male subjects. The AVI is superior to the CI, LAP, VAI, and BAI in assessing cardiometabolic risk in T2DM patients. CONCLUSIONS: Our study indicated that measuring adiponectin and A/R index, together with measuring AVI as a measure of general volume, can be used as surrogates in the evaluation of high cardiovascular risk among T2DM patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Curr Health Sci J Año: 2022 Tipo del documento: Article Pais de publicación: Rumanía
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Curr Health Sci J Año: 2022 Tipo del documento: Article Pais de publicación: Rumanía