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Role of SHP2 (PTPN11) in glycoprotein VI-dependent thrombus formation: Improved platelet responsiveness by the allosteric drug SHP099 in Noonan syndrome patients.
Fernández, Delia I; Diender, Marije; Hermida-Nogueira, Lidia; Huang, Jingnan; Veiras, Sonia; Henskens, Yvonne M C; Te Loo, Maroeska W M; Heemskerk, Johan W M; Kuijpers, Marijke J E; García, Ángel.
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  • Fernández DI; Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, and Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain; Department of Biochemistry, CARIM, Maastricht University, 6200
  • Diender M; Department of Pediatric Hematology, Amalia children's hospital, Radboud UMC, Nijmegen, the Netherlands.
  • Hermida-Nogueira L; Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, and Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain.
  • Huang J; Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, and Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain; Department of Biochemistry, CARIM, Maastricht University, 6200
  • Veiras S; Department of Anesthesiology and Intensive Care Medicine, Clinical University Hospital of Santiago, Santiago de Compostela, Spain.
  • Henskens YMC; Central Diagnostic Laboratory, Unit for Hemostasis and Transfusion, Maastricht University Medical Centre(+), Maastricht, the Netherlands.
  • Te Loo MWM; Department of Pediatric Hematology, Amalia children's hospital, Radboud UMC, Nijmegen, the Netherlands.
  • Heemskerk JWM; Department of Biochemistry, CARIM, Maastricht University, 6200 MD Maastricht, the Netherlands; Synapse Research Institute, Kon. Emmaplein 7, 6217 KD, Maastricht, the Netherlands.
  • Kuijpers MJE; Department of Biochemistry, CARIM, Maastricht University, 6200 MD Maastricht, the Netherlands; Thrombosis Expertise Centre, Heart and Vascular Centre, Maastricht University Medical Centre(+), Maastricht, the Netherlands. Electronic address: Marijke.Kuijpers@maastrichtuniversity.nl.
  • García Á; Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, and Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain.
Thromb Res ; 228: 105-116, 2023 08.
Article en En | MEDLINE | ID: mdl-37302266
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombosis / Síndrome de Noonan Límite: Humans Idioma: En Revista: Thromb Res Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombosis / Síndrome de Noonan Límite: Humans Idioma: En Revista: Thromb Res Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos