Beyond Natural Immune Repertoires: Synthetic Antibodies.
Cold Spring Harb Protoc
; 2024(4): pdb.top107768, 2024 Apr 01.
Article
en En
| MEDLINE
| ID: mdl-37295822
Synthetic antibody libraries, in which the antigen-binding sites are precisely designed, offer unparalleled precision in antibody engineering, exceeding the potential of natural immune repertoires and constituting a novel generation of research tools and therapeutics. Recent advances in artificial intelligence-driven technologies and their integration into synthetic antibody discovery campaigns hold the promise to further streamline and effectively develop antibodies. Here, we provide an overview of synthetic antibodies. Our associated protocol describes how to develop highly diverse and functional synthetic antibody phage display libraries.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inteligencia Artificial
/
Biblioteca de Péptidos
Tipo de estudio:
Guideline
Idioma:
En
Revista:
Cold Spring Harb Protoc
Año:
2024
Tipo del documento:
Article
País de afiliación:
Canadá
Pais de publicación:
Estados Unidos