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Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Chen, Xinhong; Wolfe, Damien A; Bindu, Dhanesh Sivadasan; Zhang, Mengying; Taskin, Naz; Goertsen, David; Shay, Timothy F; Sullivan, Erin E; Huang, Sheng-Fu; Ravindra Kumar, Sripriya; Arokiaraj, Cynthia M; Plattner, Viktor M; Campos, Lillian J; Mich, John K; Monet, Deja; Ngo, Victoria; Ding, Xiaozhe; Omstead, Victoria; Weed, Natalie; Bishaw, Yeme; Gore, Bryan B; Lein, Ed S; Akrami, Athena; Miller, Cory; Levi, Boaz P; Keller, Annika; Ting, Jonathan T; Fox, Andrew S; Eroglu, Cagla; Gradinaru, Viviana.
Afiliación
  • Chen X; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Wolfe DA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Bindu DS; Department of Cell Biology, Duke University Medical Center, Durham, NC, 27710, USA.
  • Zhang M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Taskin N; Allen Institute for Brain Science, Seattle, WA, USA.
  • Goertsen D; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Shay TF; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Sullivan EE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Huang SF; Department of Neurosurgery, Clinical Neuroscience Center, Zürich University Hospital, University of Zürich, Zürich, Switzerland.
  • Ravindra Kumar S; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Arokiaraj CM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Plattner VM; Sainsbury Wellcome Centre, University College London, London, UK.
  • Campos LJ; Department of Psychology and California National Primate Research Center, University of California, Davis, Davis, CA, 95616, USA.
  • Mich JK; Allen Institute for Brain Science, Seattle, WA, USA.
  • Monet D; Allen Institute for Brain Science, Seattle, WA, USA.
  • Ngo V; Cortical Systems and Behavior Lab, University of California San Diego, La Jolla, CA, 92039, USA.
  • Ding X; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
  • Omstead V; Allen Institute for Brain Science, Seattle, WA, USA.
  • Weed N; Allen Institute for Brain Science, Seattle, WA, USA.
  • Bishaw Y; Allen Institute for Brain Science, Seattle, WA, USA.
  • Gore BB; Allen Institute for Brain Science, Seattle, WA, USA.
  • Lein ES; Allen Institute for Brain Science, Seattle, WA, USA.
  • Akrami A; Sainsbury Wellcome Centre, University College London, London, UK.
  • Miller C; Cortical Systems and Behavior Lab, University of California San Diego, La Jolla, CA, 92039, USA.
  • Levi BP; Allen Institute for Brain Science, Seattle, WA, USA.
  • Keller A; Department of Neurosurgery, Clinical Neuroscience Center, Zürich University Hospital, University of Zürich, Zürich, Switzerland.
  • Ting JT; Neuroscience Center Zürich, University of Zürich and ETH Zürich, Zürich, Switzerland.
  • Fox AS; Allen Institute for Brain Science, Seattle, WA, USA.
  • Eroglu C; Department of Physiology and Biophysics, University of Washington, Seattle, WA, USA.
  • Gradinaru V; Department of Psychology and California National Primate Research Center, University of California, Davis, Davis, CA, 95616, USA.
Nat Commun ; 14(1): 3345, 2023 06 08.
Article en En | MEDLINE | ID: mdl-37291094
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Roedores / Células Endoteliales Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Roedores / Células Endoteliales Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido