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Right Ventricular Reverse Remodeling After Tricuspid Valve Surgery for Significant Tricuspid Regurgitation.
Galloo, Xavier; Meucci, Maria Chiara; Stassen, Jan; Dietz, Marlieke F; Prihadi, Edgard A; van der Bijl, Pieter; Ajmone Marsan, Nina; Braun, Jerry; Bax, Jeroen J; Delgado, Victoria.
Afiliación
  • Galloo X; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Meucci MC; Department of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.
  • Stassen J; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Dietz MF; Department of Cardiovascular and Thoracic Sciences, Catholic University of the Sacred Heart, Rome, Italy.
  • Prihadi EA; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • van der Bijl P; Department of Cardiology, Jessa Hospital, Hasselt, Belgium.
  • Ajmone Marsan N; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Braun J; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Bax JJ; Hartcentrum, Ziekenhuis Netwerk Antwerpen (ZNA) Middelheim, Antwerp, Belgium.
  • Delgado V; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Struct Heart ; 7(1): 100101, 2023 Jan.
Article en En | MEDLINE | ID: mdl-37275311
Background: Changes in right ventricular (RV) dimensions and function after tricuspid valve (TV) surgery and their association with long-term outcomes remain largely unexplored. The current study evaluated RV reverse remodeling, based on changes in RV dimensions and function, after TV surgery for significant (moderate or severe) tricuspid regurgitation (TR) and their association with outcome. Methods: A total of 121 patients (mean age 63 ± 12 years, 47% males) with significant TR treated with TV surgery were included in this analysis. The population was stratified by tertiles of percentage reduction of RV end-systolic area (RVESA) and absolute change of RV fractional area change (RVFAC). Five-year mortality rates were compared across the tertiles of RV remodeling and independent associates of mortality were investigated. Results: Tertile 3 consisted of patients presenting with a reduction in RVESA ≥17.2% and an improvement in RVFAC ≥2.3% after TV surgery. Cumulative survival rates were significantly better in patients within tertile 3 of RVESA reduction: 90% vs. 49% for tertile 1 and 69% for tertile 2 (log-rank p = 0.002) and within tertile 3 of RVFAC improvement: 87% vs. 57% for tertile 1 and 65% for tertile 2 (log-rank p = 0.02). Tertiles 3 of RVESA reduction and RVFAC improvement were both independently associated with better survival after TV surgery compared to tertiles 1 (hazard ratio: 0.221 [95% CI: 0.074-0.658] and 0.327 [95% CI: 0.118-0.907], respectively). Conclusions: The extent of RV reverse remodeling, based on reduction in RVESA and improvement in RVFAC, was associated with better survival at 5-year follow-up of TV surgery for significant TR.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Struct Heart Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Struct Heart Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos