Your browser doesn't support javascript.
loading
Genomic Architecture of Hybrid Male Sterility in a Species Without Sex Chromosomes (Tigriopus californicus, Copepoda: Harpacticoida).
Olsen, Kevin C; Lima, Thiago G; Barreto, Felipe S; Burton, Ronald S.
Afiliación
  • Olsen KC; Scripps Institution of Oceanography, Marine Biology Research Division, University of California San Diego, La Jolla, California, USA.
  • Lima TG; Scripps Institution of Oceanography, Marine Biology Research Division, University of California San Diego, La Jolla, California, USA.
  • Barreto FS; Department of Integrative Biology, Oregon State University, Corvallis, Oregon, USA.
  • Burton RS; Scripps Institution of Oceanography, Marine Biology Research Division, University of California San Diego, La Jolla, California, USA.
Genome Biol Evol ; 15(6)2023 06 01.
Article en En | MEDLINE | ID: mdl-37260390
Sterility among hybrids is one of the most prevalent forms of reproductive isolation delineating species boundaries and is expressed disproportionately in heterogametic XY males. While hybrid male sterility (HMS) due to the "large X effect" is a well-recognized mechanism of reproductive isolation, it is less clear how HMS manifests in species that lack heteromorphic sex chromosomes. We evaluated differences in allele frequencies at approximately 460,000 SNPs between fertile and sterile F2 interpopulation male hybrids to characterize the genomic architecture of HMS in a species without sex chromosomes (Tigriopus californicus). We tested associations between HMS and mitochondrial-nuclear and/or nuclear-nuclear signatures of incompatibility. Genomic regions associated with HMS were concentrated on a single chromosome with the same primary 2-Mbp regions identified in one pair of reciprocal crosses. Gene Ontology analysis revealed that annotations associated with spermatogenesis were the most overrepresented within the implicated region, with nine protein-coding genes connected with this process found in the quantitative trait locus of chromosome 2. Our results indicate that a narrow genomic region was associated with the sterility of male hybrids in T. californicus and suggest that incompatibilities among select nuclear loci may replace the large X effect when sex chromosomes are absent.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Copépodos / Infertilidad Masculina Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Genome Biol Evol Asunto de la revista: BIOLOGIA / BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Copépodos / Infertilidad Masculina Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Genome Biol Evol Asunto de la revista: BIOLOGIA / BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido