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Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)3-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds.
Bao, Xiaobo; Yu, Wei; Wang, Lilin; Dong, Xu; Wang, Guoli; Chen, Weilin; Li, Fei; Chen, Dongyin.
Afiliación
  • Bao X; College of Pharmacy, Jiangsu Vocational College of Medicine Yancheng 224005 China.
  • Yu W; School of Pharmacy, Nanjing Medical University Nanjing 211166 China chendongyin@njmu.edu.cn kldlf@njmu.edu.cn chenweilin@njmu.edu.cn.
  • Wang L; Sir Run Run Hospital, Nanjing Medical University Nanjing 211166 China.
  • Dong X; School of Pharmacy, Nanjing Medical University Nanjing 211166 China chendongyin@njmu.edu.cn kldlf@njmu.edu.cn chenweilin@njmu.edu.cn.
  • Wang G; School of Pharmacy, Nanjing Medical University Nanjing 211166 China chendongyin@njmu.edu.cn kldlf@njmu.edu.cn chenweilin@njmu.edu.cn.
  • Chen W; School of Pharmacy, Nanjing Medical University Nanjing 211166 China chendongyin@njmu.edu.cn kldlf@njmu.edu.cn chenweilin@njmu.edu.cn.
  • Li F; School of Pharmacy, Nanjing Medical University Nanjing 211166 China chendongyin@njmu.edu.cn kldlf@njmu.edu.cn chenweilin@njmu.edu.cn.
  • Chen D; School of Pharmacy, Nanjing Medical University Nanjing 211166 China chendongyin@njmu.edu.cn kldlf@njmu.edu.cn chenweilin@njmu.edu.cn.
RSC Adv ; 13(23): 15942-15946, 2023 May 22.
Article en En | MEDLINE | ID: mdl-37250229
The Er(OTf)3-catalyzed cascade cyclization reaction of para-quinone methides (p-QMs) with various 1,3-dicarbonyl compounds has been developed, which efficiently constructed a series of versatile 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes. Herein, we not only propose a novel cyclization strategy of p-QMs, but also provide an easy access to structurally diverse coumarins and chromenes.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: RSC Adv Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: RSC Adv Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido