Degradation of neuromuscular junction contributes to muscle weakness but not physical compromise in chronic obstructive pulmonary disease patients taking lipids-lowering medications.

Qaisar, Rizwan; Karim, Asima; Muhammad, Tahir; Alkahtani, Shaea A; Kamli, Hossam; Ahmad, Firdos

Qaisar, Rizwan; Karim, Asima; Muhammad, Tahir; Alkahtani, Shaea A; Kamli, Hossam; Ahmad, Firdos.

Afiliación

Qaisar R; Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Cardiovascular Research Group, Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates. Electronic address: rqaisar@sharjah.ac.ae.
Karim A; Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Muhammad T; Department of Biochemistry, Gomal Medical College, Gomal University, Dera Ismail Khan, 30130, Pakistan.
Alkahtani SA; Exercise Physiology Department, College of Sport Sciences and Physical Activity, King Saud University, Riyadh, 11451, Saudi Arabia.
Kamli H; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, 61421, Saudi Arabia.
Ahmad F; Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Cardiovascular Research Group, Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Biomedical Sciences, College of Health Scien

Respir Med ; 215: 107298, 2023.

Article en En | MEDLINE | ID: mdl-37245649

Asunto(s)

Inhibidores de Hidroximetilglutaril-CoA Reductasas; Enfermedad Pulmonar Obstructiva Crónica; Humanos; Masculino; Persona de Mediana Edad; Anciano; Fuerza de la Mano/fisiología; Inhibidores de Hidroximetilglutaril-CoA Reductasas/efectos adversos; Enfermedad Pulmonar Obstructiva Crónica/tratamiento farmacológico; Debilidad Muscular; Unión Neuromuscular; Lípidos

Palabras clave

C-terminal agrin-fragment 22; Chronic obstructive pulmonary disease; Handgrip strength; Neuromuscular junction; Short physical performance battery; Statins

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Hidroximetilglutaril-CoA Reductasas / Enfermedad Pulmonar Obstructiva Crónica Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Respir Med Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido

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