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Oxidative Stress, Reductive Stress and Antioxidants in Vascular Pathogenesis and Aging.
Mladenov, Mitko; Lubomirov, Lubomir; Grisk, Olaf; Avtanski, Dimiter; Mitrokhin, Vadim; Sazdova, Iliyana; Keremidarska-Markova, Milena; Danailova, Yana; Nikolaev, Georgi; Konakchieva, Rossitza; Gagov, Hristo.
Afiliación
  • Mladenov M; Faculty of Natural Sciences and Mathematics, Institute of Biology, "Ss. Cyril and Methodius" University, P.O. Box 162, 1000 Skopje, North Macedonia.
  • Lubomirov L; Institute of Physiology, Brandenburg Medical School Theodor Fontane, 16816 Neuruppin, Germany.
  • Grisk O; Institute of Physiology, Brandenburg Medical School Theodor Fontane, 16816 Neuruppin, Germany.
  • Avtanski D; Friedman Diabetes Institute, Lenox Hill Hospital, Northwell Health, 110 E 59th Street, New York, NY 10003, USA.
  • Mitrokhin V; Department of Physiology, Pirogov Russian National Research Medical University, 1 Ostrovityanova Street, 117997 Moscow, Russia.
  • Sazdova I; Department of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.
  • Keremidarska-Markova M; Department of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.
  • Danailova Y; Department of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.
  • Nikolaev G; Department of Cell and Developmental Biology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.
  • Konakchieva R; Department of Cell and Developmental Biology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.
  • Gagov H; Department of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.
Antioxidants (Basel) ; 12(5)2023 May 19.
Article en En | MEDLINE | ID: mdl-37237992
This review is focused on the mechanisms that regulate health, disease and aging redox status, the signal pathways that counteract oxidative and reductive stress, the role of food components and additives with antioxidant properties (curcumin, polyphenols, vitamins, carotenoids, flavonoids, etc.), and the role of the hormones irisin and melatonin in the redox homeostasis of animal and human cells. The correlations between the deviation from optimal redox conditions and inflammation, allergic, aging and autoimmune responses are discussed. Special attention is given to the vascular system, kidney, liver and brain oxidative stress processes. The role of hydrogen peroxide as an intracellular and paracrine signal molecule is also reviewed. The cyanotoxins ß-N-methylamino-l-alanine (BMAA), cylindrospermopsin, microcystins and nodularins are introduced as potentially dangerous food and environment pro-oxidants.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies Idioma: En Revista: Antioxidants (Basel) Año: 2023 Tipo del documento: Article Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies Idioma: En Revista: Antioxidants (Basel) Año: 2023 Tipo del documento: Article Pais de publicación: Suiza