Structure-Function Analysis of the S-Glycosylation Reaction in the Biosynthesis of Lincosamide Antibiotics.

Mori, Takahiro; Sun, Xin; Kadlcik, Stanislav; Janata, Jiri; Abe, Ikuro

Mori, Takahiro; Sun, Xin; Kadlcik, Stanislav; Janata, Jiri; Abe, Ikuro.

Afiliación

Mori T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Sun X; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Kadlcik S; PRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama, 332-0012, Japan.
Janata J; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Abe I; Institute of Microbiology, The Czech Academy of Sciences, Prague, Czech Republic, Videnska 1083, 14000, Prague, Czech Republic.

Angew Chem Int Ed Engl ; 62(29): e202304989, 2023 07 17.

Article en En | MEDLINE | ID: mdl-37222528

Asunto(s)

Antibacterianos; Lincomicina; Glicosilación; Antibacterianos/química; Lincosamidas/química; Lincosamidas/metabolismo; Lincomicina/química; Glicosiltransferasas/metabolismo; Cristalografía por Rayos X

Palabras clave

Biosynthesis; Glycosyltransferase; Lincosamides; Natural product; X-ray Crystallography

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lincomicina / Antibacterianos Idioma: En Revista: Angew Chem Int Ed Engl Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania

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