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Human AGEs: an interactive spatio-temporal visualization and database of human archeogenomics.
Ciecierski, Lukasz; Stolarek, Ireneusz; Figlerowicz, Marek.
Afiliación
  • Ciecierski L; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
  • Stolarek I; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
  • Figlerowicz M; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Nucleic Acids Res ; 51(W1): W269-W273, 2023 07 05.
Article en En | MEDLINE | ID: mdl-37216609
Archeogenomics is a rapidly growing interdisciplinary research field driven by the development of techniques that enable the acquisition and analysis of ancient DNA (aDNA). Recent advances in aDNA studies have contributed significantly to increasing our understanding of the natural history of humans. One of the most significant challenges facing archeogenomics is the integration of highly heterogeneous genomic, archeological, and anthropological data and their comprehensive analysis, considering changes that occur in time and space. Only this complex approach can explain the relationship between past populations in the context of migration or cultural development. To address these challenges, we developed a Human AGEs web server. It focuses on creating comprehensive spatiotemporal visualizations of genomic, archeogenomic, and archeological information, which can be provided by the user or loaded from a graph database. The interactive map application at the center of Human AGEs can display multiple layers of data in various forms, such as bubble charts, pie charts, heatmaps, or tag clouds. These visualizations can be modified using various clustering, filtering, and styling options, and the map state can be exported to a high-resolution image or saved as a session file for later use. Human AGEs, along with their tutorial, are accessible at https://archeogenomics.eu/.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genómica Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2023 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genómica Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2023 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Reino Unido