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Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome (PCOS): A Comprehensive Review.
Di Lorenzo, M; Cacciapuoti, N; Lonardo, M S; Nasti, G; Gautiero, C; Belfiore, A; Guida, B; Chiurazzi, M.
Afiliación
  • Di Lorenzo M; Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
  • Cacciapuoti N; Infectious Diseases and Gender Medicine Unit, Cotugno Hospital, AO Dei Colli, Naples, Italy.
  • Lonardo MS; Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
  • Nasti G; Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
  • Gautiero C; Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
  • Belfiore A; Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
  • Guida B; Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
  • Chiurazzi M; Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
Curr Nutr Rep ; 12(3): 527-544, 2023 09.
Article en En | MEDLINE | ID: mdl-37213054
PURPOSE OF REVIEW: Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women of reproductive age worldwide. This disease causes menstrual, metabolic, and biochemical abnormalities such as hyperandrogenism, oligo-anovulatory menstrual cycles, polycystic ovary, hyperleptinemia, insulin resistance (IR), and cardiometabolic disorders, often associated with overweight or obesity and visceral adiposity. RECENT FINDINGS: The etiology and pathophysiology of PCOS are not yet fully understood, but insulin seems to play a key role in this disease. PCOS shares an inflammatory state with other chronic diseases such as obesity, type II diabetes, and cardiovascular diseases; however, recent studies have shown that a healthy nutritional approach can improve IR and metabolic and reproductive functions, representing a valid therapeutic strategy to ameliorate PCOS symptomatology. This review aimed to summarize and collect evidence about different nutritional approaches such as the Mediterranean diet (MedDiet) and the ketogenic diet (KD), as well as bariatric surgery and nutraceutical supplementation as probiotics, prebiotics, and synbiotics, among the others, used in patients with PCOS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Resistencia a la Insulina / Hiperandrogenismo / Diabetes Mellitus Tipo 2 Límite: Female / Humans Idioma: En Revista: Curr Nutr Rep Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Resistencia a la Insulina / Hiperandrogenismo / Diabetes Mellitus Tipo 2 Límite: Female / Humans Idioma: En Revista: Curr Nutr Rep Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos