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Increase in hypoglycaemia and hyperglycaemia in people with diabetes admitted to hospital during COVID-19 pandemic.
Ruan, Yue; Mercuri, Luca; Papadimitriou, Dimitri; Galdikas, Algirdas; Roadknight, Gail; Davies, Jim; Glampson, Ben; Mayer, Erik; Hill, Neil E; Rea, Rustam.
Afiliación
  • Ruan Y; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK.
  • Mercuri L; Imperial Clinical Analytics, Research & Evaluation Centre, Imperial College Healthcare NHS Trust, London, UK; NIHR Imperial Biomedical Research Centre, London, UK.
  • Papadimitriou D; Imperial Clinical Analytics, Research & Evaluation Centre, Imperial College Healthcare NHS Trust, London, UK; NIHR Imperial Biomedical Research Centre, London, UK.
  • Galdikas A; Imperial Clinical Analytics, Research & Evaluation Centre, Imperial College Healthcare NHS Trust, London, UK; NIHR Imperial Biomedical Research Centre, London, UK.
  • Roadknight G; Oxford NIHR Biomedical Research Centre, Oxford, UK.
  • Davies J; Oxford NIHR Biomedical Research Centre, Oxford, UK.
  • Glampson B; Imperial Clinical Analytics, Research & Evaluation Centre, Imperial College Healthcare NHS Trust, London, UK; NIHR Imperial Biomedical Research Centre, London, UK.
  • Mayer E; Imperial Clinical Analytics, Research & Evaluation Centre, Imperial College Healthcare NHS Trust, London, UK; NIHR Imperial Biomedical Research Centre, London, UK.
  • Hill NE; Endocrinology & Diabetes, Imperial College Healthcare NHS Trust, London, UK. Electronic address: neil.hill@nhs.net.
  • Rea R; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK; Oxford NIHR Biomedical Research Centre, Oxford, UK.
J Diabetes Complications ; 37(7): 108474, 2023 07.
Article en En | MEDLINE | ID: mdl-37207507
BACKGROUND: We used detailed information on patients with diabetes admitted to hospital to determine differences in clinical outcomes before and during the COVID-19 pandemic in the UK. METHODS: The study used electronic patient record data from Imperial College Healthcare NHS Trust. Hospital admission data for patients coded for diabetes was analysed over three time periods: pre-pandemic (31st January 2019-31st January 2020), Wave 1 (1st February 2020-30th June 2020), and Wave 2 (1st September 2020-30th April 2021). We compared clinical outcomes including glycaemia and length of stay. RESULTS: We analysed data obtained from 12,878, 4008 and 7189 hospital admissions during the three pre-specified time periods. The incidence of Level 1 and Level 2 hypoglycaemia was significantly higher during Waves 1 and 2 compared to the pre-pandemic period (25 % and 25.1 % vs. 22.9 % for Level 1 and 11.7 % and 11.5 % vs. 10.3 % for Level 2). The incidence of hyperglycaemia was also significantly higher during the two waves. The median hospital length of stay increased significantly (4.1[1.6, 9.8] and 4.0[1.4, 9.4] vs. 3.5[1.2, 9.2] days). CONCLUSIONS: During the COVID-19 pandemic in the UK, hospital in-patients with diabetes had a greater number of hypoglycaemic/hyperglycaemic episodes and an increased length of stay when compared to the pre-pandemic period. This highlights the necessity for a focus on improved diabetes care during further significant disruptions to healthcare systems and ensuring minimisation of the impact on in-patient diabetes services. SUMMARY: Diabetes is associated with poorer outcomes from COVID-19. However the glycaemic control of inpatients before and during the COVID-19 pandemic is unknown. We found the incidence of hypoglycaemia and hyperglycaemia was significantly higher during the pandemic highlighting the necessity for a focus on improved diabetes care during further pandemics.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / COVID-19 / Hiperglucemia / Hipoglucemia Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Diabetes Complications Asunto de la revista: ENDOCRINOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / COVID-19 / Hiperglucemia / Hipoglucemia Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Diabetes Complications Asunto de la revista: ENDOCRINOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos