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Comparison between radical surgery and chemoradiotherapy in patients with cervical esophageal cancer: a propensity score matched analysis.
Qi, Kang; Lin, Gang; Liu, Haibo; Zhang, Xining; Chen, Zhimao; Li, Jian.
Afiliación
  • Qi K; Department of Thoracic surgery, Peking University First Hospital, Xishiku str.8, 100034 Xicheng District, Beijing, China. qikang923@hotmail.com.
  • Lin G; Department of Thoracic surgery, Peking University First Hospital, Xishiku str.8, 100034 Xicheng District, Beijing, China.
  • Liu H; Department of Thoracic surgery, Peking University First Hospital, Xishiku str.8, 100034 Xicheng District, Beijing, China.
  • Zhang X; Department of Thoracic surgery, Peking University First Hospital, Xishiku str.8, 100034 Xicheng District, Beijing, China.
  • Chen Z; Department of Thoracic surgery, Peking University First Hospital, Xishiku str.8, 100034 Xicheng District, Beijing, China.
  • Li J; Department of Thoracic surgery, Peking University First Hospital, Xishiku str.8, 100034 Xicheng District, Beijing, China.
BMC Surg ; 23(1): 119, 2023 May 11.
Article en En | MEDLINE | ID: mdl-37170089
BACKGROUND: The prognostic value of radical surgery (RS) and chemoradiotherapy (CRT) for cervical esophageal cancer (CEC) was estimated using the Surveillance, Epidemiology and End Results (SEER) database after 1:1 propensity score matching (PSM). METHODS: This retrospective study used SEER data of CEC patients between 2004 and 2015. The prognostic effects on cancer-specific survival (CSS) were evaluated using multivariate cox regression analysis following radical surgery or CRT before and after PSM. The subgroup analysis of CSS is carried out according to T stages. RESULTS: A total of 440 patients met the eligibility criteria. Three hundred and fifty-six(80.9%)patients underwent chemoradiotherapy, and eighty-four (19.1%) patients underwent radical surgery. There were significant differences between patients of radical surgery and CRT groups with regard to the tumor grade, histology and N stage. After PSM, 80 matched pairs (A total of 160 patients) were selected. Multivariable cox regression analysis revealed no difference in the CSS of patients that underwent either radical surgery or CRT before [hazard ratio (HR): 0.955, 95% CI: 0.704-1.295, P = 0.766] and after PSM (HR: 0.767, 95% CI: 0.512-1.149, P = 0.198). Subgroup analysis revealed no significant difference in CSS between patients with radical surgery and CRT groups for all T stages (T 1-4, all P > 0.05). CONCLUSIONS: This analysis revealed that the prognostic outcomes in patients with cervical esophageal cancer were comparable between radical surgery and CRT.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Neoplasias del Cuello Uterino Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: BMC Surg Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Neoplasias del Cuello Uterino Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: BMC Surg Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido