Predictive stability, novel HPLC-MS analysis and semi-automatic compounding process for the emergency implementation of a production line of pancuronium in injectable solution.

Merienne, Camille; Filali, Samira; Marchand, Chloé; Lapras, Benjamine; Paillet, Carole; Pirot, Fabrice

Merienne, Camille; Filali, Samira; Marchand, Chloé; Lapras, Benjamine; Paillet, Carole; Pirot, Fabrice.

Afiliación

Merienne C; Service Pharmaceutique, Plateforme FRIPHARM, Groupement Hospitalier Centre, Hôpital Edouard Herriot, Place d'Arsonval, F-69437 Lyon Cedex 03, France. Electronic address: camille.merienne@chu-lyon.fr.
Filali S; Service Pharmaceutique, Plateforme FRIPHARM, Groupement Hospitalier Centre, Hôpital Edouard Herriot, Place d'Arsonval, F-69437 Lyon Cedex 03, France.
Marchand C; Service Pharmaceutique, Plateforme FRIPHARM, Groupement Hospitalier Centre, Hôpital Edouard Herriot, Place d'Arsonval, F-69437 Lyon Cedex 03, France.
Lapras B; Service Pharmaceutique, Plateforme FRIPHARM, Groupement Hospitalier Centre, Hôpital Edouard Herriot, Place d'Arsonval, F-69437 Lyon Cedex 03, France.
Paillet C; Service Pharmaceutique, Plateforme FRIPHARM, Groupement Hospitalier Centre, Hôpital Edouard Herriot, Place d'Arsonval, F-69437 Lyon Cedex 03, France.
Pirot F; Service Pharmaceutique, Plateforme FRIPHARM, Groupement Hospitalier Centre, Hôpital Edouard Herriot, Place d'Arsonval, F-69437 Lyon Cedex 03, France; Laboratoire de Recherche et Développement de Pharmacie Galénique Industrielle, UMR 5305, Plateforme Fripharm, Faculté de Pharmacie, Université Claude

Eur J Pharm Sci ; 187: 106464, 2023 Aug 01.

Article en En | MEDLINE | ID: mdl-37169099

Asunto(s)

COVID-19; Pancuronio; Humanos; Cromatografía Líquida de Alta Presión/métodos; Estudios Prospectivos; Pandemias; Estabilidad de Medicamentos; Composición de Medicamentos

Palabras clave

Accelerated stability study; Drug compounding; Drug stability; High-performance liquid chromatography; Mass spectrometry; Pancuronium

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancuronio / COVID-19 Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Eur J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos

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