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A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors.
Melero, Ignacio; Tanos, Tamara; Bustamante, Mariana; Sanmamed, Miguel F; Calvo, Emiliano; Moreno, Irene; Moreno, Victor; Hernandez, Tatiana; Martinez Garcia, Maria; Rodriguez-Vida, Alejo; Tabernero, Josep; Azaro, Analia; Ponz-Sarvisé, Mariano; Spanggaard, Iben; Rohrberg, Kristoffer; Guarin, Ernesto; Nüesch, Eveline; Davydov, Iakov I; Ooi, Chiahuey; Duarte, José; Chesne, Evelyne; McIntyre, Christine; Ceppi, Maurizio; Cañamero, Marta; Krieter, Oliver.
Afiliación
  • Melero I; Department of Immunology and Immunotherapy, Clinica Universidad de Navarra and CIMA, 31008 Pamplona, Spain.
  • Tanos T; CIBERONC, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  • Bustamante M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland.
  • Sanmamed MF; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland.
  • Calvo E; Department of Immunology and Immunotherapy, Clinica Universidad de Navarra and CIMA, 31008 Pamplona, Spain.
  • Moreno I; CIBERONC, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  • Moreno V; Department of Medical Oncology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.
  • Hernandez T; START Madrid-CIOCC, Centro Integral Oncológico Clara Campal, 28050 Madrid, Spain.
  • Martinez Garcia M; START Madrid-CIOCC, Centro Integral Oncológico Clara Campal, 28050 Madrid, Spain.
  • Rodriguez-Vida A; START Madrid-FJD, Hospital Fundación Jiménez Díaz, 28040 Madrid, Spain.
  • Tabernero J; START Madrid-FJD, Hospital Fundación Jiménez Díaz, 28040 Madrid, Spain.
  • Azaro A; Department of Medical Oncology, Hospital del Mar-CIBERONC, 08003 Barcelona, Spain.
  • Ponz-Sarvisé M; Department of Medical Oncology, Hospital del Mar-CIBERONC, 08003 Barcelona, Spain.
  • Spanggaard I; CIBERONC, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  • Rohrberg K; Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), 08035 Barcelona, Spain.
  • Guarin E; Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), 08035 Barcelona, Spain.
  • Nüesch E; CIBERONC, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  • Davydov II; Department of Medical Oncology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.
  • Ooi C; Department of Oncology, Rigshospitalet University Hospital of Copenhagen, 2100 Copenhagen, Denmark.
  • Duarte J; Department of Oncology, Rigshospitalet University Hospital of Copenhagen, 2100 Copenhagen, Denmark.
  • Chesne E; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland.
  • McIntyre C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland.
  • Ceppi M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland.
  • Cañamero M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland.
  • Krieter O; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland.
Sci Transl Med ; 15(695): eabp9229, 2023 05 10.
Article en En | MEDLINE | ID: mdl-37163618
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Neoplasias Límite: Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Neoplasias Límite: Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos