An assessment of EGFR and HER2 inhibitors with structure activity relationship of fused pyrimidine derivatives for breast cancer: a brief review.

Dhiwar, Prasad Sanjay; Purawarga Matada, Gurubasavaraja Swamy; Pal, Rohit; Singh, Ekta; Ghara, Abhishek; Maji, Lalmohan; Sengupta, Sindhuja; Andhale, Ganesh

Dhiwar, Prasad Sanjay; Purawarga Matada, Gurubasavaraja Swamy; Pal, Rohit; Singh, Ekta; Ghara, Abhishek; Maji, Lalmohan; Sengupta, Sindhuja; Andhale, Ganesh.

Afiliación

Dhiwar PS; Intergrated drug discovery center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.
Purawarga Matada GS; Intergrated drug discovery center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.
Pal R; Intergrated drug discovery center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.
Singh E; Intergrated drug discovery center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.
Ghara A; Intergrated drug discovery center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.
Maji L; Intergrated drug discovery center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.
Sengupta S; Intergrated drug discovery center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, India.
Andhale G; Department of Pharmaceutical Chemistry, Alard College of Pharmacy, Pune, India.

J Biomol Struct Dyn ; 42(3): 1564-1581, 2024.

Article en En | MEDLINE | ID: mdl-37158086

Asunto(s)

Antineoplásicos; Neoplasias de la Mama; Animales; Humanos; Femenino; Neoplasias de la Mama/tratamiento farmacológico; Estructura Molecular; Ensayos de Selección de Medicamentos Antitumorales; Antineoplásicos/farmacología; Antineoplásicos/química; Inhibidores de Proteínas Quinasas/farmacología; Inhibidores de Proteínas Quinasas/química; Relación Estructura-Actividad; Proliferación Celular; Pirimidinas/farmacología; Pirimidinas/química; Línea Celular Tumoral; Receptores ErbB

Palabras clave

ATP; EGFR; HER2; SAR; pyrimidine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: J Biomol Struct Dyn Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

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