Adriamycin downregulates the expression of KLF4 in cardiomyocytes in vitro and contributes to impaired cardiac energy metabolism in Adriamycin-induced cardiomyopathy.

Mohan, Uma Priya; Pichiah, P B Tirupathi; Arunachalam, Sankarganesh

Mohan, Uma Priya; Pichiah, P B Tirupathi; Arunachalam, Sankarganesh.

Afiliación

Mohan UP; Centre for Cardiovascular and Adverse Drug Reactions, Department of Biotechnology, School of Bio, Chemical and Processing Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Virudhunagar Dt., Tamilnadu, 626126 India.
Pichiah PBT; Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu 620024 India.
Arunachalam S; Centre for Cardiovascular and Adverse Drug Reactions, Department of Biotechnology, School of Bio, Chemical and Processing Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Virudhunagar Dt., Tamilnadu, 626126 India.

3 Biotech ; 13(5): 162, 2023 May.

Article en En | MEDLINE | ID: mdl-37152000

Palabras clave

Adriamycin; Cardiac energetics; KLF4; Mitochondrial dysfunction; PDK4 and PGC-1α; PPARα; PPARß; PPARÎ³

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: 3 Biotech Año: 2023 Tipo del documento: Article Pais de publicación: Alemania

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