Overview of human B-cell development and antibody deficiencies.
J Immunol Methods
; 519: 113485, 2023 08.
Article
en En
| MEDLINE
| ID: mdl-37150477
B cells are a key component of the humoral (antibody-mediated) immune response which is responsible for defense against a variety of pathogens. Here we provide an overview of the current understanding of B cell development and function and briefly describe inborn errors of immunity associated with B cell development defects which can manifest as immune deficiency, malignancy, autoimmunity, or allergy. The knowledge and application of B cell biology are essential for laboratory evaluation and clinical assessment of these B cell disorders.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Centro Germinal
/
Inmunidad Humoral
Límite:
Humans
Idioma:
En
Revista:
J Immunol Methods
Año:
2023
Tipo del documento:
Article
Pais de publicación:
Países Bajos