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Venom phenotype conservation suggests integrated specialization in a lizard-eating snake.
Heptinstall, Tucker C; Strickland, Jason L; Rosales-Garcia, Ramses A; Rautsaw, Rhett M; Simpson, Cassandra L; Nystrom, Gunnar S; Ellsworth, Schyler A; Hogan, Michael P; Borja, Miguel; Fernandes Campos, Pollyanna; Grazziotin, Felipe G; Rokyta, Darin R; Junqueira-de-Azevedo, Inácio L M; Parkinson, Christopher L.
Afiliación
  • Heptinstall TC; Department of Biological Sciences, Clemson University, Clemson, SC, 29634, USA.
  • Strickland JL; Department of Biological Sciences, Clemson University, Clemson, SC, 29634, USA; Department of Biology, University of South Alabama, Mobile, AL, 36688, USA.
  • Rosales-Garcia RA; Department of Biological Sciences, Clemson University, Clemson, SC, 29634, USA.
  • Rautsaw RM; Department of Biological Sciences, Clemson University, Clemson, SC, 29634, USA; School of Biological Sciences, Washington State University, Pullman, WA, 99164, USA; Department of Integrative Biology, University of South Florida, Tampa, FL, 33620, USA.
  • Simpson CL; Department of Biological Sciences, Clemson University, Clemson, SC, 29634, USA.
  • Nystrom GS; Department of Biological Science, Florida State University, Tallahassee, FL, 32306, USA.
  • Ellsworth SA; Department of Biological Science, Florida State University, Tallahassee, FL, 32306, USA.
  • Hogan MP; Department of Biological Science, Florida State University, Tallahassee, FL, 32306, USA.
  • Borja M; Facultad de Ciencias Biológicas, Universdad Juárez del Estado de Durango, Av. Universidad s/n. Fracc. Filadelfia, C.P. 35070, Gómez Palacio, Dgo., Mexico.
  • Fernandes Campos P; Laboratório de Toxinologia Aplicada, Instituto Butantan, São Paulo, São Paulo, Brazil.
  • Grazziotin FG; Laboratório Especial de Colecões Zoológicas, Instituto Butantan, São Paulo, São Paulo, Brazil.
  • Rokyta DR; Department of Biological Science, Florida State University, Tallahassee, FL, 32306, USA.
  • Junqueira-de-Azevedo ILM; Laboratório de Toxinologia Aplicada, Instituto Butantan, São Paulo, São Paulo, Brazil.
  • Parkinson CL; Department of Biological Sciences, Clemson University, Clemson, SC, 29634, USA; Department of Forestry and Environmental Conservation, Clemson University, Clemson, SC, 29634, USA. Electronic address: viper@clemson.edu.
Toxicon ; 229: 107135, 2023 Jun 15.
Article en En | MEDLINE | ID: mdl-37146732
Biological specialization reduces the size of niche space while increasing efficiency in the use of available resources. Specialization often leads to phenotypic changes via natural selection aligning with niche space constraints. Commonly observed changes are in size, shape, behavior, and traits associated with feeding. One often selected trait for dietary specialization is venom, which, in snakes, often shows variation dependent on diet across and within species. The Neotropical Blunt-headed Treesnake (Imantodes cenchoa) is a highly specialized, rear-fanged, arboreal, lizard hunter that displays a long thin body, enlarged eyes, and a large Duvernoy's gland. However, toxin characterization of I. cenchoa has never been completed. Here, we use RNA-seq and mass spectrometry to assemble, annotate, and analyze the venom gland transcriptomes of four I. cenchoa from across their range. We find a lack of significant venom variation at the sequence and expression levels, suggesting venom conservation across the species. We propose this conservation provides evidence of a specialized venom repertoire, adapted to maximize efficiency of capturing and processing lizards. Importantly, this study provides the most complete venom gland transcriptomes of I. cenchoa and evidence of venom specialization in a rear-fanged snake, giving insight into selective pressures of venom across all snake species.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Toxinas Biológicas / Colubridae / Lagartos Límite: Animals Idioma: En Revista: Toxicon Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Toxinas Biológicas / Colubridae / Lagartos Límite: Animals Idioma: En Revista: Toxicon Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido