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Short-term outcomes of heart transplant patients bridged with Impella 5.5 ventricular assist device.
Haddad, Osama; Sareyyupoglu, Basar; Goswami, Rohan M; Bitargil, Macit; Patel, Parag C; Jacob, Samuel; El-Sayed Ahmed, Magdy M; Leoni Moreno, Juan Carlos; Yip, Daniel S; Landolfo, Kevin; Pham, Si M.
Afiliación
  • Haddad O; Department of Cardiothoracic Surgery, Mayo Clinic Hospital, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
  • Sareyyupoglu B; Department of Cardiothoracic Surgery, Mayo Clinic Hospital, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
  • Goswami RM; Department of Transplantation, Mayo Clinic Hospital, Jacksonville, FL, USA.
  • Bitargil M; Department of Cardiothoracic Surgery, Mayo Clinic Hospital, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
  • Patel PC; Department of Transplantation, Mayo Clinic Hospital, Jacksonville, FL, USA.
  • Jacob S; Department of Cardiothoracic Surgery, Mayo Clinic Hospital, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
  • El-Sayed Ahmed MM; Department of Cardiothoracic Surgery, Mayo Clinic Hospital, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
  • Leoni Moreno JC; Department of Transplantation, Mayo Clinic Hospital, Jacksonville, FL, USA.
  • Yip DS; Department of Transplantation, Mayo Clinic Hospital, Jacksonville, FL, USA.
  • Landolfo K; Department of Cardiothoracic Surgery, Mayo Clinic Hospital, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
  • Pham SM; Department of Cardiothoracic Surgery, Mayo Clinic Hospital, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
ESC Heart Fail ; 10(4): 2298-2306, 2023 08.
Article en En | MEDLINE | ID: mdl-37137732
AIMS: We sought to investigate the outcomes of heart transplant patients supported with Impella 5.5 temporary mechanical circulatory support. METHODS AND RESULTS: Patient demographics, perioperative data, hospital timeline, and haemodynamic parameters were followed during initial admission, Impella support, and post-transplant period. Vasoactive-inotropic score, primary graft failure, and complications were recorded. Between March 2020 and March 2021, 16 advanced heart failure patients underwent Impella 5.5 temporary left ventricular assist device support through axillary approach. Subsequently, all these patients had heart transplantation. All patients were either ambulatory or chair bound during their temporary mechanical circulatory support until heart transplantation. Patients were kept on Impella support median of 19 days (3-31) with the median lactate dehydrogenase level of 220 (149-430). All Impella devices were removed during heart transplantation. During Impella support, patients had improved renal function with median creatinine serum level of 1.55 mg/dL decreased to 1.25 (P = 0.007), pulmonary artery pulsatility index scores increased from 2.56 (0.86-10) to 4.2 (1.3-10) (P = 0.048), and right ventricular function improved (P = 0.003). Patients maintained improved renal function and favourable haemodynamics after their heart transplantation as well. All patients survived without any significant morbidity after their heart transplantation. CONCLUSIONS: Impella 5.5 temporary left ventricular assist device optimizes care of heart transplant recipients providing superior haemodynamic support, mobility, improved renal function, pulmonary haemodynamics, and right ventricular function. Utilizing Impella 5.5 as a direct bridging strategy to heart transplantation resulted in excellent outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corazón Auxiliar / Trasplante de Corazón / Insuficiencia Cardíaca Tipo de estudio: Etiology_studies / Observational_studies Límite: Humans Idioma: En Revista: ESC Heart Fail Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corazón Auxiliar / Trasplante de Corazón / Insuficiencia Cardíaca Tipo de estudio: Etiology_studies / Observational_studies Límite: Humans Idioma: En Revista: ESC Heart Fail Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido