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Dose pulmonary hemorrhage increase the risk of bronchopulmonary dysplasia in very low birth weight infants?
Pan, Jing-Jing; Zou, Yun-Su; Tong, Mei-Ling; Wang, Jing; Zhou, Xiao-Yu; Cheng, Rui; Yang, Yang.
Afiliación
  • Pan JJ; Department of Neonates, Jiangsu Provincial Maternal and Child Health Hospital, Nanjing, Jiangsu, P.R. China.
  • Zou YS; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
  • Tong ML; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, P.R. China.
  • Wang J; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, P.R. China.
  • Zhou XY; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
  • Cheng R; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
  • Yang Y; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
J Matern Fetal Neonatal Med ; 36(1): 2206941, 2023 Dec.
Article en En | MEDLINE | ID: mdl-37121909
OBJECTIVE: To evaluate the association between pulmonary hemorrhage and bronchopulmonary dysplasia (BPD) in very low birth weight infants (VLBWIs). METHODS: The study participants were all VLBW newborns admitted from January 1, 2019 to December 31, 2021. The BPD subjects finally included were VLBWIs who survived until the diagnosis was established. This study was divided into pulmonary hemorrhage group (PH group, n = 35) and non-pulmonary hemorrhage group (Non-PH group, n = 190). RESULTS: By univariate analysis it was found that premature rupture of membranes, tracheal intubation in the delivery room, duration of mechanical ventilation, course of invasive ventilation (≥3 courses), pulmonary surfactant (>1 dose), medically and surgically treated patent ductus arteriosus, grade III-IV RDS, early onset sepsis, BPD and moderate to severe BPD showed significant differences between groups (p < .05). By Multivariate analysis, pulmonary hemorrhage did not increase the risks of BPD and moderate to severe BPD (adjusted OR for BPD = 1.710, 95% CI 0.581-5.039; adjusted OR for moderate to severe BPD = 2.401, 95% CI 0.736-7.834). CONCLUSION: It suggests that pulmonary hemorrhage is not associated with the development of BPD and moderate to severe BPD in VLBWIs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Displasia Broncopulmonar / Conducto Arterioso Permeable Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Female / Humans / Infant / Newborn Idioma: En Revista: J Matern Fetal Neonatal Med Asunto de la revista: OBSTETRICIA / PERINATOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Displasia Broncopulmonar / Conducto Arterioso Permeable Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Female / Humans / Infant / Newborn Idioma: En Revista: J Matern Fetal Neonatal Med Asunto de la revista: OBSTETRICIA / PERINATOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido