ALOX5 inhibition protects against dopaminergic neurons undergoing ferroptosis.

Li, Kun; Wang, Meng; Huang, Zi-Han; Wang, Min; Sun, Wan-Yang; Kurihara, Hiroshi; Huang, Rui-Ting; Wang, Rong; Huang, Feng; Liang, Lei; Li, Yi-Fang; Duan, Wen-Jun; He, Rong-Rong

Li, Kun; Wang, Meng; Huang, Zi-Han; Wang, Min; Sun, Wan-Yang; Kurihara, Hiroshi; Huang, Rui-Ting; Wang, Rong; Huang, Feng; Liang, Lei; Li, Yi-Fang; Duan, Wen-Jun; He, Rong-Rong.

Afiliación

Li K; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Wang M; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Huang ZH; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Wang M; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Sun WY; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Kurihara H; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Huang RT; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Wang R; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
Huang F; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Chinese Medicine, Kunming 650500, China.
Liang L; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Li YF; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
Duan WJ; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti
He RR; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Consti

Pharmacol Res ; 193: 106779, 2023 07.

Article en En | MEDLINE | ID: mdl-37121496

Asunto(s)

Ferroptosis; Enfermedad de Parkinson; Animales; Ratones; Neuronas Dopaminérgicas; Cromatografía Liquida; Espectrometría de Masas en Tándem

Palabras clave

(-)-Clausenamide; (-)-Clausenamide (PubChem CID: 9904294); 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (PubChem CID: 1388); 3-Methyladenine (PubChem CID: 135398661); 5-Lipoxygenase; Erastin (PubChem CID: 11214940); Ferroptosis; Ferrostatin-1 (PubChem CID: 4068248); L-Buthionine Sulfoximine (PubChem CID: 119565); Lipid peroxides; Necrostatin-1 (PubChem CID: 2828334); Oxidative damage; Parkinson's disease; Selegiline (PubChem CID: 26757); Sulfasalazine (PubChem CID: 5339); Z-VAD(OMe)-FMK (PubChem CID: 5497174)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Ferroptosis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos

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