Capsaicin Reduces Cancer Stemness and Inhibits Metastasis by Downregulating <i>SOX2</i> and <i>EZH2</i> in Osteosarcoma.

Chen, Zhi-Yu; Huang, Huan-Huan; Li, Qiao-Chu; Zhan, Fang-Biao; Wang, Ling-Bang; He, Tao; Yang, Chao-Hua; Wang, Yang; Zhang, Yuan; Quan, Zheng-Xue

Capsaicin Reduces Cancer Stemness and Inhibits Metastasis by Downregulating SOX2 and EZH2 in Osteosarcoma.

Chen, Zhi-Yu; Huang, Huan-Huan; Li, Qiao-Chu; Zhan, Fang-Biao; Wang, Ling-Bang; He, Tao; Yang, Chao-Hua; Wang, Yang; Zhang, Yuan; Quan, Zheng-Xue.

Afiliación

Chen ZY; Orthopedic Laboratory of Chongqing Medical University, Chongqing 40016, P. R. China.
Huang HH; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P. R. China.
Li QC; Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P. R. China.
Zhan FB; Orthopedic Laboratory of Chongqing Medical University, Chongqing 40016, P. R. China.
Wang LB; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P. R. China.
He T; Department of Orthopedics, Chongqing University Three Gorges Hospital, Wanzhou, Chongqing 404000, P. R. China.
Yang CH; Orthopedic Laboratory of Chongqing Medical University, Chongqing 40016, P. R. China.
Wang Y; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P. R. China.
Zhang Y; Orthopedic Laboratory of Chongqing Medical University, Chongqing 40016, P. R. China.
Quan ZX; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P. R. China.

Am J Chin Med ; 51(4): 1041-1066, 2023.

Article en En | MEDLINE | ID: mdl-37120706

Asunto(s)

Neoplasias Óseas; Osteosarcoma; Humanos; Capsaicina/farmacología; Capsaicina/uso terapéutico; Capsaicina/metabolismo; Proliferación Celular/genética; Línea Celular Tumoral; Osteosarcoma/tratamiento farmacológico; Osteosarcoma/genética; Neoplasias Óseas/tratamiento farmacológico; Neoplasias Óseas/genética; Neoplasias Óseas/metabolismo; Células Madre Neoplásicas/patología; Proteína Potenciadora del Homólogo Zeste 2/metabolismo; Proteína Potenciadora del Homólogo Zeste 2/farmacología; Factores de Transcripción SOXB1/genética; Factores de Transcripción SOXB1/metabolismo; Factores de Transcripción SOXB1/farmacología

Palabras clave

Cancer Stem Cells; Capsaicin; Metastasis; Osteosarcoma; mRNAsi

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Óseas / Osteosarcoma Límite: Humans Idioma: En Revista: Am J Chin Med Año: 2023 Tipo del documento: Article Pais de publicación: Singapur

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