Apatinib combined with olaparib induces ferroptosis via a p53-dependent manner in ovarian cancer.

Yue, Wang; Yupeng, Gu; Jun, Cao; Kui, Jiang

Yue, Wang; Yupeng, Gu; Jun, Cao; Kui, Jiang.

Afiliación

Yue W; Department of Medical Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Yupeng G; Department of Medical Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Jun C; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian, 116044, China. caojunly@163.com.
Kui J; Department of Medical Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. jk0411@163.com.

J Cancer Res Clin Oncol ; 149(11): 8681-8689, 2023 Sep.

Article en En | MEDLINE | ID: mdl-37120435

Asunto(s)

Ferroptosis; Neoplasias Ováricas; Femenino; Humanos; Apoptosis; Línea Celular Tumoral; Factor 2 Relacionado con NF-E2/metabolismo; Neoplasias Ováricas/tratamiento farmacológico; Neoplasias Ováricas/genética; Neoplasias Ováricas/metabolismo; Proteína p53 Supresora de Tumor/genética; Proteína p53 Supresora de Tumor/metabolismo

Palabras clave

Apatinib; Ferroptosis; Nrf2; Olaparib; p53

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Ferroptosis Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: J Cancer Res Clin Oncol Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania

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