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Methodology for risk-based monitoring of contaminants in food - A case study in cereals and fish.
Hobé, R G; van Asselt, E D; van den Heuvel, L; Hoek-van den Hil, E F; van der Fels-Klerx, H J.
Afiliación
  • Hobé RG; Wageningen Food Safety Research (WFSR), Wageningen University & Research, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands. Electronic address: rosan.hobe@wur.nl.
  • van Asselt ED; Wageningen Food Safety Research (WFSR), Wageningen University & Research, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands.
  • van den Heuvel L; Wageningen Food Safety Research (WFSR), Wageningen University & Research, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands.
  • Hoek-van den Hil EF; Wageningen Food Safety Research (WFSR), Wageningen University & Research, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands.
  • van der Fels-Klerx HJ; Wageningen Food Safety Research (WFSR), Wageningen University & Research, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands.
Food Res Int ; 168: 112791, 2023 06.
Article en En | MEDLINE | ID: mdl-37120237
In this study, a methodology was developed that can be used as input for risk-based monitoring plans for chemical contaminants in food products. The novel methodology was applied to a case study in which cereals and fish were evaluated simultaneously for the possible presence of mycotoxins and heavy metals. The methodology was based on hazard quotients that were estimated by dividing the daily intake - using concentrations of the contaminants in the different food products and consumption of the respective products combined per product group - by the health based guidance value (HBGV) or reference points used for assessing potential health concerns (RPHC). The most relevant hazard-product combinations were further ranked based on the volume of import of the ingredients, per import country and a defined contaminant prevalence level per country. For fish, the hazard quotients were around ten times lower compared to the highest hazard quotients in cereals. Consumption of molluscs, mackerel-type fish and herring-type fish contaminated with mercury contributed most to the HBGV or RPHC. The top 25 hazard-product combinations for various age groups included: aflatoxin B1 in combination with wheat, rice (products), maize (products), and pasta, zearalenone in combination with wheat (products), T2/HT2-toxin in combination with rice (products), and DON in combination with wheat (products). The methodology presented showed to be useful in identifying the most relevant hazard-food-age group combinations and the most relevant import countries linked to these that should be included in the monitoring. As such, the method can help risk managers in establishing risk-based monitoring programs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Zearalenona / Micotoxinas Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Food Res Int Año: 2023 Tipo del documento: Article Pais de publicación: Canadá

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Zearalenona / Micotoxinas Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Food Res Int Año: 2023 Tipo del documento: Article Pais de publicación: Canadá