Enhancing the Anti-tumor Potency of a Novel Siglec-15 Antibody by Engineering its Fc-mediated Effector Functions.

Ding, Huandi; Yao, Bing; Ci, Lei; Feng, Jing; Ouyang, Pingkai; Chen, Guoguang; Hui, Xiwu; Zhou, Demin

Ding, Huandi; Yao, Bing; Ci, Lei; Feng, Jing; Ouyang, Pingkai; Chen, Guoguang; Hui, Xiwu; Zhou, Demin.

Afiliación

Ding H; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing.
Yao B; CSPC Megalith Biopharmaceutical Co. Ltd, Shijiazhuang.
Ci L; CSPC Megalith Biopharmaceutical Co. Ltd, Shijiazhuang.
Feng J; School of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing.
Ouyang P; Shanghai Engineering Research Center for Model Organisms, SMOC, Shanghai, China.
Chen G; CSPC Megalith Biopharmaceutical Co. Ltd, Shijiazhuang.
Hui X; School of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing.
Zhou D; School of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing.

J Immunother ; 46(5): 161-169, 2023 06 01.

Article en En | MEDLINE | ID: mdl-37103472

Asunto(s)

Neoplasias; Animales; Ratones; Anticuerpos Monoclonales/farmacología; Anticuerpos Monoclonales/uso terapéutico; Inmunoglobulina G; Inmunoglobulinas; Proteínas de la Membrana; Neoplasias/terapia; Lectinas Similares a la Inmunoglobulina de Unión a Ácido Siálico; Humanos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

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