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Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17.
Chan, Yen-Ju; Hsiao, George; Wan, Wang-Nok; Yang, Tsung-Min; Tsai, Chi-Hao; Kang, Jaw-Jou; Lee, Yu-Cheng; Fang, Te-Chao; Cheng, Yu-Wen; Li, Ching-Hao.
Afiliación
  • Chan YJ; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, 250 Wuxing Street, Taipei, 110, Taiwan.
  • Hsiao G; School of Pharmacy, Taipei Medical University, 250 Wuxing Street, Taipei, 110, Taiwan.
  • Wan WN; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  • Yang TM; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  • Tsai CH; TMU Neuroscience Research Center, Taipei Medical University, Taipei, Taiwan.
  • Kang JJ; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, 250 Wuxing Street, Taipei, 110, Taiwan.
  • Lee YC; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, 250 Wuxing Street, Taipei, 110, Taiwan.
  • Fang TC; School of Pharmacy, Taipei Medical University, 250 Wuxing Street, Taipei, 110, Taiwan.
  • Cheng YW; Department of Ophthalmology, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Li CH; Institute of Food Safety and Health Risk Assessment, School of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Fluids Barriers CNS ; 20(1): 31, 2023 Apr 24.
Article en En | MEDLINE | ID: mdl-37095509
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Barrera Hematorretinal / Células Endoteliales Límite: Animals Idioma: En Revista: Fluids Barriers CNS Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Barrera Hematorretinal / Células Endoteliales Límite: Animals Idioma: En Revista: Fluids Barriers CNS Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Reino Unido