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Human health risk assessment of potentially toxic elements in the breast milk consumed by infants in Western Iran.
Sharafi, Kiomars; Nakhaee, Samaneh; Azadi, Nammam Ali; Mansouri, Borhan; Miri Kermanshahi, Saba; Paknahad, Maedeh; Habibi, Yazdan.
Afiliación
  • Sharafi K; Research Center for Environmental Determinants of Health (RCEDH), Research Institute for Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Nakhaee S; Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.
  • Azadi NA; Biostatistics Department, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
  • Mansouri B; Substance Abuse Prevention Research Center, Research Institute for Health, Kermanshah University of Medical Sciences, Kermanshah, Iran. borhanmansouri@yahoo.com.
  • Miri Kermanshahi S; Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Paknahad M; Substance Abuse Prevention Research Center, Research Institute for Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Habibi Y; Substance Abuse Prevention Research Center, Research Institute for Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Sci Rep ; 13(1): 6656, 2023 04 24.
Article en En | MEDLINE | ID: mdl-37095309
This study aimed to assess the human health risk of some toxic metals/metalloids [lead (Pb), mercury (Hg), cadmium (Cd), nickel (Ni), chromium (Cr), and arsenic (As)] on infants via consumption of the breast milk of women living in urban areas of Kermanshah city, west of Iran. After collecting milk samples, the carcinogenic and non-carcinogenic risk assessment as well as uncertainty analysis of toxic metal levels were carried out. The order of concentration of heavy metals/metalloids in the breast milk samples was Cr (41.07 ± 23.19) > Ni (19.25 ± 11.81) > Pb (11.5 ± 4.48) > As (1.96 ± 2.04) > Cd (.72 ± 0.42) > Hg (0.31 ± 0.26). The results revealed that the levels of Cr and Pb in the breast milk samples were exceeded the World Health Organization (WHO) tolerable daily intake. In the breast milk samples a high levels of one of the trace elements As, Cd, Cr, Pb, and Ni were observed (over 73%) and in 40% of them the levels of Cr, Pb, Cd, As, and Ni were all above WHO tolerable daily intake. Moreover, the As-related point assessment of target risk factor (THQ) was higher than the allowable limit only for 1-month-old male neonates and 2-month-old female neonates (THQ > 1). In addition, Cr-related THQ scores were higher at all age and gender groups (THQ > 1). In conclusion, our findings suggest a potential risk of some metals for infants via the consumption of mothers' breast milk.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arsénico / Metales Pesados / Mercurio Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Female / Humans / Infant / Male / Newborn País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arsénico / Metales Pesados / Mercurio Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Female / Humans / Infant / Male / Newborn País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido