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Early detection of poor glycemic control in patients with diabetes mellitus in sub-Saharan Africa: a cohort study in Mozambique.
Ciccacci, Fausto; Manto, Andrea; Morviducci, Lelio; Lanti, Fabiana; Majid, Noorjehan; Agy, Mustafa; Massango, Cacilda; Orlando, Stefano; Guidotti, Giovanni; Marazzi, Maria Cristina.
Afiliación
  • Ciccacci F; UniCamillus, Saint Camillus International University of Health Sciences, Rome, Italy.
  • Manto A; Azienda Sanitaria Locale Roma 1, Rome, Italy.
  • Morviducci L; Azienda Sanitaria Locale Roma 1 - Santo Spirito Hospital-Diabetology and Dietology Unit, Rome, Italy.
  • Lanti F; Azienda Sanitaria Locale Roma 1, Rome, Italy.
  • Majid N; DREAM Program, Community of Sant'Egidio, Maputo, Mozambique.
  • Agy M; DREAM Program, Community of Sant'Egidio, Maputo, Mozambique.
  • Massango C; DREAM Program, Community of Sant'Egidio, Maputo, Mozambique.
  • Orlando S; University of Rome Tor Vergata, Department of Biomedicine and Prevention, Rome, Italy.
  • Guidotti G; Azienda Sanitaria Locale Roma 1, Rome, Italy.
  • Marazzi MC; Libera Università Maria Ss. Assunta, Rome, Italy.
Afr Health Sci ; 22(4): 127-132, 2022 Dec.
Article en En | MEDLINE | ID: mdl-37092081
Introduction: WHO estimates 422 million cases of diabetes mellitus worldwide. Mozambique has the second-highest mortality related to DM in the African region.Objectives of the present study are to provide data about a DM care service in Mozambique and to evaluate early outcomes of treatment. Methods: The new patients diagnosed with DM in a two-years period in a health centre in Maputo (Mozambique) were included in a retrospective cohort study. Fasting blood glucose (FBG), waist circumference (WC) and BMI were collected at baseline and after three months. Results: 188 patients were enrolled. Median BMI, WC and FBG at baseline were respectively 28 kg/m2(Inter Quartile Range [IQR]23.4-31.8), 98cm (IQR 87-105) and 209mg/dL (IQR 143-295). A non-pharmacological intervention was prescribed for six patients, while 182 patients received metformin 500 mg b.i.d. FBG was significantly reduced at control (226[±103.7]mg/dL vs 186[±93.2]mg/dL, p<0.000); however, glycemic control was reached in 74 patients (39.4%); not controlled patients changed regimen. Elderly patients had a higher glycemic control (adjusted Odds Ratio 2.50, 95% CI 1.11-5.06, p=0.002). Conclusion: Strategies for early detection of scarce glycemic control are feasible in Mozambique and could lead to prompt regimen switch; an invasive therapeutic approach could be preferable in selected cases to achieve control.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Hiperglucemia Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies / Screening_studies Límite: Aged / Humans País/Región como asunto: Africa Idioma: En Revista: Afr Health Sci Asunto de la revista: MEDICINA / SERVICOS DE SAUDE Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Uganda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Hiperglucemia Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies / Screening_studies Límite: Aged / Humans País/Región como asunto: Africa Idioma: En Revista: Afr Health Sci Asunto de la revista: MEDICINA / SERVICOS DE SAUDE Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Uganda