[Results of the management of kidney cancer with extension into the inferior vena cava: A retrospective, single-center, observational study]. / Résultats de la prise en charge des cancers du rein avec extension dans la veine cave inférieure : étude observationnelle rétrospective monocentrique.
Prog Urol
; 33(6): 333-343, 2023 May.
Article
en Fr
| MEDLINE
| ID: mdl-37076361
OBJECTIVES: The aim of our study was to evaluate the morbidity and mortality, as well as the oncogical results of patients who had undergone surgical procedure for a kidney cancer with thrombus extension into the inferior vena cava. MATERIALS AND METHODS: Between January 2004 and April 2020, 57 patients were operated by enlarged nephrectomy with thrombectomy for kidney cancer with thrombus extension in the inferior vena cava. Twelve patients (21%) with the use of cardiopulmonary bypass because the thrombus was upper than the sus-hepatic veins. Twenty-three patients (40.4%) were metastatic at diagnosis. RESULTS: Perioperative mortality was 10.5%, without difference according to surgical technique. Morbidity during hospitalization was 58%, without difference according to surgical technique. Median follow-up was 40.8±40.1months. Overall survival at 2 and 5years was 60% and 28%, respectively. At 5years, the principal prognostic factor was the metastatic status at diagnosis, in multivariate analysis (OR: 0.15, P=0.03). Progression free survival mean was 28.2±40.2months. Progression free survival at 2 and 5years was 28% and 18%, respectively. All the patients who were metastatic at diagnosis had a recurrence in an average time of 5.7months (median of 3months). Thirteen percent of patients can be considered cured at the end of the study. CONCLUSION: Morbidity and mortality of this surgery remain important. The metastatic status at diagnosis has appeared to be the principal prognostic factor on the survival of these patients. LEVEL OF EVIDENCE: Level 4: retrospective study.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trombosis
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Carcinoma de Células Renales
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Neoplasias Renales
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Células Neoplásicas Circulantes
Tipo de estudio:
Etiology_studies
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Observational_studies
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Prognostic_studies
Límite:
Humans
Idioma:
Fr
Revista:
Prog Urol
Asunto de la revista:
UROLOGIA
Año:
2023
Tipo del documento:
Article
Pais de publicación:
Francia