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Non-linear relationship between dietary vitamin E intake and cognitive performance in older adults.
Li, W; Li, S; Zhuang, W; Shang, Y; Yan, G; Lu, J; Chen, Z; Lyu, J.
Afiliación
  • Li W; Department of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China; Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
  • Li S; Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
  • Zhuang W; Department of Rehabilitation, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
  • Shang Y; Department of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China.
  • Yan G; Department of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China.
  • Lu J; Department of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China.
  • Chen Z; Department of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China. Electronic address: zm120tchzm@qq.com.
  • Lyu J; Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization, Guangzhou, Guangdong, China. Electronic address: lyujun2020@jnu.edu.cn.
Public Health ; 219: 10-17, 2023 Jun.
Article en En | MEDLINE | ID: mdl-37075487
OBJECTIVES: This study aimed to explore the relationship between dietary vitamin E (VE) intake and cognitive function in older adults. STUDY DESIGN: This was a cross-sectional study. METHODS: We applied data from the National Health and Nutrition Examination Survey obtained during 2011-2014 that met our requirements. The cognitive ability assessments included the Consortium to Establish a Registry for Alzheimer's Disease Word Learning (CERAD-WL) and Delayed Recall (CERAD-DR) tests, the animal fluency test, the Digit Symbol Substitution Test, and a composite z-score calculated by summing z-scores of individual tests. We used binary logistic regression analysis to explore the relationship between VE intake and cognitive performance. The results are reported using odds ratios and 95% confidence intervals. Our study also included sex-stratified analyses and sensitivity analysis. A restricted cubic splines model was used to evaluate the dose-response relationship between dietary VE intake and cognitive function. RESULTS: This study found that a higher intake of dietary VE was associated with a lower risk of cognitive impairment in patients. Sensitivity analysis shows stable results. The results of the gender stratification analysis showed that dietary VE intake was negatively related to the risk of cognitive disorder among females. An irregular L-shaped dose-response relationship was observed between dietary VE intake and cognitive impairment risk. CONCLUSIONS: Dietary VE intake was negatively related to the risk of cognitive disorder in older adults, with a higher VE intake lowering the risk.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cognición / Dieta Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Public Health Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cognición / Dieta Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Public Health Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos