Birth weight and bone mineral density at 18-19 years: birth cohort 1997-1998.
Rev Saude Publica
; 57: 9, 2023.
Article
en En, Pt
| MEDLINE
| ID: mdl-37075393
OBJECTIVE: To analyze the association between birth weight and bone mineral density (BMD) in adolescence. METHODS: A birth cohort study in São Luís, Maranhão, using data from two moments: at birth and at 18-19 years. Exposure was the birth weight in grams, continuously analyzed. The outcome was BMD, using the Z-score index (whole body) measured by double X-ray densitometry (Dexa). A theoretical model was constructed in acyclic graphs to identify the minimum set of adjustment variables - household income, the mother knowing how to read and write at the time of birth, prenatal care, tobacco use during pregnancy, and parity - to evaluate the association between birth weight and bone mineral density in adolescence. Multiple linear regression was used in Stata 14.0 software. A 5% significance level was adopted. RESULTS: From 2,112 adolescents, 8.2% had low birth weight and 2.8% had a low BMD for their age. The mean full-body Z-score was 0.19 (± 1.00). The highest birth weight was directly and linearly associated with BMD values in adolescence (Coef.: 0.10; 95%CI: 0.02-0.18), even after adjustment for the variables household income (Coef.: -0.33; 95%CI: -0.66-0.33) and the mother knowing how to read and write (Coef.: 0.23%; 95%CI: 0.03-0.43). CONCLUSION: Although after adjusting the variables the association attenuated, birth weight positively and linearly relates to BMD in adolescence.
Texto completo
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118403
- https://dx.doi.org/10.11606/s1518-8787.2023057004179
- http://www.scielo.br/scielo.php?script=sci_arttext&nrm=iso&lng=pt&tlng=pt&pid=S0034-89102023000100204
- http://www.scielosp.org/scielo.php?script=sci_arttext&nrm=iso&lng=pt&tlng=pt&pid=S0034-89102023000100204
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Densidad Ósea
/
Cohorte de Nacimiento
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Female
/
Humans
/
Newborn
/
Pregnancy
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
/
Pt
Revista:
Rev Saude Publica
Año:
2023
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil