Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos.

Yamada, Yutaro; Noguchi, Takuya; Suzuki, Midori; Yamada, Mayuka; Hirata, Yusuke; Matsuzawa, Atsushi

Yamada, Yutaro; Noguchi, Takuya; Suzuki, Midori; Yamada, Mayuka; Hirata, Yusuke; Matsuzawa, Atsushi.

Afiliación

Yamada Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Noguchi T; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Suzuki M; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Yamada M; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Hirata Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Matsuzawa A; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan. Electronic address: atsushi.matsuzawa.c6@tohoku.ac.jp.

J Biol Chem ; 299(6): 104710, 2023 06.

Article en En | MEDLINE | ID: mdl-37060999

Asunto(s)

Parthanatos; Proteína Sequestosoma-1/metabolismo; Estrés Oxidativo; Muerte Celular; Proteínas HSP70 de Choque Térmico/genética; Proteínas HSP70 de Choque Térmico/metabolismo; Azufre/metabolismo

Palabras clave

70 kDa heat shock protein (Hsp70); aggresome; p62 (sequestosome 1(SQSTM1)); parthanatos; reactive sulfur species

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Parthanatos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google